Chronic kidney disease (CKD) affects> 10% of the world population, with increasing
prevalence in middle age. The risk for CKD is dependent on the number of functioning …

Physical inactivity is a scourge to human health, promoting metabolic disease and muscle
wasting. Interestingly, multiple ecological niches have relaxed investment into physical …

Since practically a century ago, the insulin pathway was discovered in both vertebrates and
invertebrates, implying an evolutionarily ancient origin. After a century of research, it is now …

The Characidae family of fish is composed of commercially important species for which little
is known about the regulation of feeding. Fish are ectotherms so that their body temperature …

Starvation causes the accumulation of lipid droplets in the liver, a somewhat counterintuitive
phenomenon that is nevertheless conserved from flies to humans. Much like fatty liver …

Sleep is an essential and evolutionarily conserved process that affects many biological
functions that are also strongly regulated by cellular metabolism. The interdependence …

In vitro assays are crucial tools for gaining detailed insights into various biological
processes, including metabolism. Cave morphs of the river‐dwelling fish species, Astyanax …

It has become clear that circadian clocks in peripheral tissues play important functions.
Disruption of the circadian clock in skeletal muscle, for example, results in insulin resistance …

The circadian clock represents a key timing system entrained by various periodic signals
that ensure synchronization with the environment. Many investigations have pointed to the …

As of April 2023, 299 species of cave and groundwater fishes have been documented
(https://cavefishes. org. uk), with many more waiting to be discovered. Despite this …