A twist of nature–the significance of atropisomers in biological systems

JE Smyth, NM Butler, PA Keller - Natural product reports, 2015 - pubs.rsc.org
Covering: up to mid-2015 Recently identified natural atropisomeric compounds with
potential medicinal applications are presented. The ability of natural receptors to possess …

Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural product …, 2014 - pubs.rsc.org
Covering: 2012. Previous review: Nat. Prod. Rep., 2013, 30, 237–323. This review covers
the literature published in 2012 for marine natural products, with 1035 citations (673 for the …

Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications

G Romano, M Almeida, A Varela Coelho, A Cutignano… - Marine Drugs, 2022 - mdpi.com
Aquatic invertebrates are a major source of biomaterials and bioactive natural products that
can find applications as pharmaceutics, nutraceutics, cosmetics, antibiotics, antifouling …

Computational prediction of chiroptical properties in structure elucidation of natural products

L Grauso, R Teta, G Esposito, M Menna… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2019 This review covers the current status of the quantum mechanical
prediction of chiroptical properties, such as electronic CD and optical rotation, as needed for …

Chemical and biological diversity of new natural products from marine sponges: a review (2009–2018)

LL Hong, YF Ding, W Zhang, HW Lin - Marine Life Science & Technology, 2022 - Springer
Marine sponges are productive sources of bioactive secondary metabolites with over 200
new compounds isolated each year, contributing 23% of approved marine drugs so far. This …

Characterization of diarylheptanoids: an emerging class of bioactive natural products

Á Alberti, E Riethmüller, S Béni - Journal of Pharmaceutical and Biomedical …, 2018 - Elsevier
Diarylheptanoids are a class of secondary plant metabolites with a wide variety of bioactivity.
Research on their phytochemistry and phytoanalysis is rapidly growing and the number of …

Anti-inflammatory activity of naturally occuring diarylheptanoids–A review

C Vanucci-Bacqué, F Bedos-Belval - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
Inflammation involving the innate and adaptive immune systems is a normal response to
infection. However, if it becomes uncontrolled, inflammation may result in autoimmune or …

Structural and Biological Insights into the Hot‐Spot Marine Natural Products Reported from 2012 to 2021

M Liu, X Zhang, G Li - Chinese Journal of Chemistry, 2022 - Wiley Online Library
Comprehensive Summary The vast marine ecosystem contains a sea of natural products,
which are potential model molecules for new drug development. With more than one …

Bioactivity and Metabolome Mining of Deep-Sea Sediment-Derived Microorganisms Reveal New Hybrid PKS-NRPS Macrolactone from Aspergillus versicolor PS108 …

F Magot, G Van Soen, L Buedenbender, F Li… - Marine Drugs, 2023 - mdpi.com
Despite low temperatures, poor nutrient levels and high pressure, microorganisms thrive in
deep-sea environments of polar regions. The adaptability to such extreme environments …

Challenges in the configuration assignment of natural products. A case-selective perspective

M Menna, C Imperatore, A Mangoni… - Natural product …, 2019 - pubs.rsc.org
Covering: up to 2018 Even today, when planar structures of natural products can be
determined with microgram samples, the configurational assignment continues to be a …