Background: The Alcohol Use Disorders Identification Test (AUDIT) has been extensively
researched to determine its capability to accurately and practically screen for alcohol …

Primary care physicians see many of the estimated 250 000 Canadians chronically infected
with the hepatitis C virus (HCV). Of this number, about one-third are unaware they are …

OBJECTIVES: It is known that liver disease can cause an imbalance in the coagulation
system, but available data on liver disease and risk of venous thromboembolism are …

Mental health problems frequently occur in chronic infection with the hepatitis C virus (HCV)
and during antiviral treatment with pegylated interferon-alpha (PegIFNα) and ribavirin …

Background Whether antidepressants prevent depression during interferon‐alpha/ribavirin
treatment for hepatitis C virus infection has yet to be established. Aim To investigate the use …

OBJECTIVES Psychiatric and substance use disorders are common in hepatitis C patients
and represent barriers to antiviral treatment. We evaluated the effect of integrating …

Studies suggest that cytokines have a role in the biology of depression. In this study, we
evaluated depression and cytokine levels in patients with and without chronic hepatitis C …

Famine and viral infection, as well as interferon therapy have been reported to increase the
risk of developing bipolar disorder. In addition, almost 100 polymorphic genes have been …

OBJECTIVES: Mental health and substance abuse (MH/SA) comorbidities are the most oft-
cited reasons for deferral from peginterferon (PegIFN) therapy for chronic hepatitis C virus …

Hepatitis C virus (HCV) infection is a major health concern in the US as well as in other
countries worldwide. Treatment issues and disease management strategies are complicated …