Hepatocellular carcinoma (HCC) is a common malignancy. Despite progress in treatment,
HCC is still one of the most lethal cancers. Therefore, deepening molecular mechanisms …

Opioid utilization for pain management is prevalent among cancer patients. There is
significant evidence describing the many effects of opioids on cancer development. Despite …

Studies have demonstrated that pigment-epithelium-derived factor (PEDF) is a robust
inhibitor of tumour growth and development, implying that this may serve as a promising …

AC1497 is an effective dual inhibitor of malate dehydrogenase 1 and 2 targeting cancer
metabolism. However, its poor aqueous solubility results in low bioavailability, limiting its …

Many studies have focused on the identification of therapeutic targets for the treatment of
certain types of cancer. Wogonin is a natural flavonoid compound that exhibits a potent anti …

Metabolism in cancer cells is rewired to generate sufficient energy equivalents and anabolic
precursors to support high proliferative activity. Within the context of these competing drives …

This study reports the start-up, acclimation, and performance of an acidogenesis process as
a biological pretreatment method to solubilize Agave bagasse fibers using the native …

Malate dehydrogenases (MDHs) sustain tumor growth and carbon metabolism by
pathogens including Plasmodium falciparum. However, clinical success of MDH inhibitors is …

We explored the effects of media and clonal variation on the lactate shift which can be
considered as one of the desirable features in CHO cell culture. Various culture profiles with …

Malate dehydrogenase (MDH) enzymes play critical roles in cellular metabolism, facilitating
the reversible conversion of malate to oxaloacetate using NAD+/NADH as a cofactor. The …