In the right place at the right time: visualizing and understanding mRNA localization
The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …
structural asymmetries in cells. Recent research has furthered our understanding of how …
RNA trafficking and subcellular localization—a review of mechanisms, experimental and predictive methodologies
RNA localization is essential for regulating spatial translation, where RNAs are trafficked to
their target locations via various biological mechanisms. In this review, we discuss RNA …
their target locations via various biological mechanisms. In this review, we discuss RNA …
[HTML][HTML] eRNAs are required for p53-dependent enhancer activity and gene transcription
CA Melo, J Drost, PJ Wijchers, H van de Werken… - Molecular cell, 2013 - cell.com
Binding within or nearby target genes involved in cell proliferation and survival enables the
p53 tumor suppressor gene to regulate their transcription and cell-cycle progression. Using …
p53 tumor suppressor gene to regulate their transcription and cell-cycle progression. Using …
The synthetic biology toolbox for tuning gene expression in yeast
H Redden, N Morse, HS Alper - FEMS yeast research, 2015 - search.proquest.com
Saccharomyces cerevisiae can serve as a key production platform for biofuels,
nutraceuticals, industrial compounds, and therapeutic proteins. Over the recent years …
nutraceuticals, industrial compounds, and therapeutic proteins. Over the recent years …
[HTML][HTML] Protein targeting to subcellular organelles via MRNA localization
BL Weis, E Schleiff, W Zerges - … et Biophysica Acta (BBA)-Molecular Cell …, 2013 - Elsevier
Cells have complex membranous organelles for the compartmentalization and regulation of
most intracellular processes. Organelle biogenesis and maintenance requires newly …
most intracellular processes. Organelle biogenesis and maintenance requires newly …
Selective fluorescent detection of RNA in living cells by using imidazolium-based cyclophane
B Shirinfar, N Ahmed, YS Park, GS Cho… - Journal of the …, 2013 - ACS Publications
A water-soluble imidazolium-based fluorescent chemosensor senses RNA selectively
through fluorescence enhancement over other biologically relevant biomolecules in …
through fluorescence enhancement over other biologically relevant biomolecules in …
Applications of computational modeling in metabolic engineering of yeast
Synthetic biology and metabolic engineering enable generation of novel cell factories that
efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating …
efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating …
The many functions of mRNA localization during normal development and disease: from pillar to post
NAL Cody, C Iampietro… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
The regulated intracellular trafficking and localized translation of mRNA molecules
represents an important and prevalent mechanism of gene regulation. This process plays a …
represents an important and prevalent mechanism of gene regulation. This process plays a …
Core Fermentation (CoFe) granules focus coordinated glycolytic mRNA localization and translation to fuel glucose fermentation
F Morales-Polanco, C Bates, J Lui, J Casson, CA Solari… - IScience, 2021 - cell.com
Glycolysis is a fundamental metabolic pathway for glucose catabolism across biology, and
glycolytic enzymes are among the most abundant proteins in cells. Their expression at such …
glycolytic enzymes are among the most abundant proteins in cells. Their expression at such …
Live-cell imaging of Pol II promoter activity to monitor gene expression with RNA IMAGEtag reporters
We describe a ribonucleic acid (RNA) reporter system for live-cell imaging of gene
expression to detect changes in polymerase II activity on individual promoters in individual …
expression to detect changes in polymerase II activity on individual promoters in individual …