Tumor evolution metrics predict recurrence beyond 10 years in locally advanced prostate cancer
J Fernandez-Mateos, GD Cresswell, N Trahearn… - Nature Cancer, 2024 - nature.com
Cancer evolution lays the groundwork for predictive oncology. Testing evolutionary metrics
requires quantitative measurements in controlled clinical trials. We mapped genomic …
requires quantitative measurements in controlled clinical trials. We mapped genomic …
Novel multiparametric magnetic resonance imaging-based deep learning and clinical parameter integration for the prediction of long-term biochemical recurrence-free …
Simple Summary Existing research on predicting biochemical recurrence after prostate
surgery has been insufficient. Here, we aimed to predict biochemical recurrence after radical …
surgery has been insufficient. Here, we aimed to predict biochemical recurrence after radical …
Models predicting survival to guide treatment decision-making in newly diagnosed primary non-metastatic prostate cancer: a systematic review
Objectives Men diagnosed with non-metastatic prostate cancer require standardised and
robust long-term prognostic information to help them decide on management. Most currently …
robust long-term prognostic information to help them decide on management. Most currently …
Prostate cancer screening: Continued controversies and novel biomarker advancements
A Tidd-Johnson, SA Sebastian, M Afaq… - Current …, 2022 - journals.lww.com
Prostate cancer (PCa) screening remains one of the most controversial topics in clinical and
public health. Despite being the second most common cancer in men worldwide …
public health. Despite being the second most common cancer in men worldwide …
A novel predictor tool of biochemical recurrence after radical prostatectomy based on a five-microRNA tissue signature
Z Zhao, S Weickmann, M Jung, M Lein, E Kilic… - Cancers, 2019 - mdpi.com
Within five to ten years after radical prostatectomy (RP), approximately 15–34% of prostate
cancer (PCa) patients experience biochemical recurrence (BCR), which is defined as …
cancer (PCa) patients experience biochemical recurrence (BCR), which is defined as …
Circular RNAs and their linear transcripts as diagnostic and prognostic tissue biomarkers in prostate cancer after prostatectomy in combination with clinicopathological …
H Rochow, M Jung, S Weickmann, B Ralla… - International Journal of …, 2020 - mdpi.com
As new biomarkers, circular RNAs (circRNAs) have been largely unexplored in prostate
cancer (PCa). Using an integrative approach, we aimed to evaluate the potential of …
cancer (PCa). Using an integrative approach, we aimed to evaluate the potential of …
Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression
JP Emond, L Lacombe, P Caron, V Turcotte… - British Journal of …, 2021 - nature.com
Abstract Background Prostate cancer (PCa) is the most common cancer in North American
men. Beyond the established contribution of androgens to disease progression, growing …
men. Beyond the established contribution of androgens to disease progression, growing …
[HTML][HTML] A new risk stratification system of prostate cancer to identify high-risk biochemical recurrence patients
X Wu, D Lv, M Eftekhar, A Khan, C Cai… - Translational …, 2020 - ncbi.nlm.nih.gov
Background Biochemical recurrence (BCR) is considered a decisive risk factor for clinical
recurrence and the metastasis of prostate cancer (PCa). Therefore, we developed and …
recurrence and the metastasis of prostate cancer (PCa). Therefore, we developed and …
[HTML][HTML] Methylation markers in prostate biopsies are prognosticators for late biochemical recurrence and therapy after surgery in prostate cancer patients
AJ Savio, S Kamdar, R Jeyapala… - The Journal of Molecular …, 2020 - Elsevier
After diagnosis of prostate cancer is confirmed by a positive biopsy, the tumor may be
surgically removed via radical prostatectomy (RP). However, many prostate cancer patients …
surgically removed via radical prostatectomy (RP). However, many prostate cancer patients …
Differential outcomes of re-stratified high-risk prostate cancer patients treated with external beam radiation therapy plus high-dose-rate brachytherapy boost
D Carignan, B Morales, P Després, W Foster… - Journal of …, 2024 - termedia.pl
Purpose: We report outcomes of high-risk prostate cancer (PCa) patients, initially classified
according to a 3-tier NCCN classification system, treated with external beam radiation …
according to a 3-tier NCCN classification system, treated with external beam radiation …