Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

The mixed lineage kinase domain-like protein (MLKL) has recently been identified as a key
RIP3 (receptor interacting protein 3) downstream component of tumour necrosis factor (TNF) …

Oxidative stress caused by an imbalanced metabolism and an excess of reactive oxygen
species (ROS) lead to a range of health disorders in humans. Our endogenous antioxidant …

The receptor-interacting serine-threonine kinase 3 (RIP3) is a key signaling molecule in the
programmed necrosis (necroptosis) pathway. This pathway plays important roles in a variety …

Reactive oxygen species (ROS) are products of normal metabolism and xenobiotic
exposure, and depending on their concentration, ROS can be beneficial or harmful to cells …

After a quarter century of rapid advances, cancer research has generated a rich and
complex body of knowledge, revealing cancer to be a disease involving dynamic changes in …

Abstract Tumour Necrosis Factor α (TNFα), is an inflammatory cytokine produced by
macrophages/monocytes during acute inflammation and is responsible for a diverse range …

Cytokines constitute a significant portion of the immuno‐and neuromodulatory messengers
that can be released by activated microglia. By virtue of potent effects on resident and …