[HTML][HTML] Antiplatelet therapy after percutaneous coronary intervention

DJ Angiolillo, M Galli, JP Collet, A Kastrati… - …, 2022 - ncbi.nlm.nih.gov
Antiplatelet therapy is key to reducing local thrombotic complications and systemic
ischaemic events among patients undergoing percutaneous coronary interventions (PCI) …

[HTML][HTML] De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

Comparison of unguided de-escalation versus guided selection of dual antiplatelet therapy after acute coronary syndrome: a systematic review and network meta …

T Kuno, T Fujisaki, S Shoji, Y Sahashi… - Circulation …, 2022 - Am Heart Assoc
Background: The benefit of dual antiplatelet therapy (DAPT) for reducing ischemic events is
greatest in the early period of acute coronary syndrome, and recent randomized controlled …

Dual antiplatelet therapy de-escalation in acute coronary syndrome: an individual patient meta-analysis

J Kang, KD Rizas, KW Park, J Chung… - European Heart …, 2023 - academic.oup.com
Aims Dual-antiplatelet therapy (DAPT) with aspirin and a potent P2Y12 inhibitor is the
standard treatment for patients with acute coronary syndrome (ACS) undergoing …

[HTML][HTML] De-escalation of antiplatelet therapy in acute coronary syndromes: why, how and when?

M Galli, DJ Angiolillo - Frontiers in cardiovascular medicine, 2022 - frontiersin.org
The synergistic blockade of the key platelet signaling pathways of cyclooxygenase-1
blockade and P2Y12 signaling by combining aspirin plus a potent P2Y12 inhibitor …

[HTML][HTML] Revascularization and medical therapy for chronic coronary syndromes: lessons learnt from recent trials, a literature review

V Pham, A Moroni, E Gall, A Benedetti… - Journal of Clinical …, 2023 - mdpi.com
Stable coronary artery disease (CAD) has recently been replaced by a new entity described
as chronic coronary syndrome (CCS). This new entity has been developed based on a …

Short-term DAPT and DAPT de-escalation strategies for patients with acute coronary syndromes: a systematic review and network meta-analysis

T Kuno, A Watanabe, S Shoji, T Fujisaki… - Circulation …, 2023 - Am Heart Assoc
BACKGROUND: Short-term (≤ 6 months) dual antiplatelet therapy (DAPT) and DAPT de-
escalation become attractive for patients with acute coronary syndrome. METHODS: A …

Safety and efficacy of ticagrelor monotherapy in patients with acute coronary syndromes undergoing percutaneous coronary intervention: an individual patient data …

U Baber, Y Jang, A Oliva, D Cao, B Vogel, G Dangas… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Dual antiplatelet therapy with a potent P2Y12 inhibitor coupled with aspirin
for 1 year is the recommended treatment for patients with acute coronary syndrome (ACS) …

[HTML][HTML] Platelets and the atherosclerotic process: an overview of new markers of platelet activation and reactivity, and their implications in primary and secondary …

M Nardin, M Verdoia, D Cao, S Nardin, E Kedhi… - Journal of Clinical …, 2023 - mdpi.com
The key role played by platelets in the atherosclerosis physiopathology, especially in the
acute setting, is ascertained: they are the main actors during thrombus formation and, thus …

Navigating the Course of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention: A Review of Guided Approaches

N Ammirabile, D Landolina… - Circulation …, 2023 - Am Heart Assoc
Dual antiplatelet therapy (DAPT) is the standard approach to prevent thrombotic events in
patients undergoing percutaneous coronary intervention and presenting with chronic or …