Emerging diagnostics and therapeutics for Alzheimer disease
WK Self, DM Holtzman - Nature medicine, 2023 - nature.com
Alzheimer disease (AD) is the most common contributor to dementia in the world, but
strategies that slow or prevent its clinical progression have largely remained elusive, until …
strategies that slow or prevent its clinical progression have largely remained elusive, until …
A comprehensive review on the role of the gut microbiome in human neurological disorders
SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …
[HTML][HTML] The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …
sustained decline in cognition. There are currently few effective disease modifying therapies …
[HTML][HTML] Role and mechanism of gut microbiota in human disease
Y Chen, J Zhou, L Wang - Frontiers in cellular and infection …, 2021 - frontiersin.org
The human gut microbiome is a huge microbial community that plays an irreplaceable role
in human life. With the further development of research, the influence of intestinal flora on …
in human life. With the further development of research, the influence of intestinal flora on …
[HTML][HTML] Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease
D Bairamian, S Sha, N Rolhion, H Sokol… - Molecular …, 2022 - Springer
Background The implication of gut microbiota in the control of brain functions in health and
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …
disease is a novel, currently emerging concept. Accumulating data suggest that the gut …
[HTML][HTML] The role of short-chain fatty acids from gut microbiota in gut-brain communication
YP Silva, A Bernardi, RL Frozza - Frontiers in endocrinology, 2020 - frontiersin.org
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the
regulation of metabolic, endocrine and immune functions. In recent years, there has been …
regulation of metabolic, endocrine and immune functions. In recent years, there has been …
Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease
Gut microbiota represents a diverse and dynamic population of microorganisms harboring
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …
the gastrointestinal tract, which influences the host health and disease. Gut microbiota …
The gut microbiome in neurological disorders
JF Cryan, KJ O'Riordan, K Sandhu, V Peterson… - The Lancet …, 2020 - thelancet.com
Research into the role of the gut microbiome in modulating brain function has rapidly
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …
[HTML][HTML] The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
[HTML][HTML] Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition
Previous studies have identified a crucial role of the gut microbiome in modifying
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …