Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare products
J Becker, CM Rohles, C Wittmann - Metabolic engineering, 2018 - Elsevier
Corynebacterium glutamicum is a major workhorse in industrial biotechnology. For the past
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …
several decades, this soil bacterium has been used to produce the amino acids l-glutamate …
Establishment of CRISPR-Cpf1-assisted gene editing tool and engineering of 4-hydroxyisoleucine biosynthesis in Corynebacterium glutamicum
R Chen, F Shi, Y Xiang, W Lai, G Ji - World Journal of Microbiology and …, 2023 - Springer
Corynebacterium glutamicum, an important industrial producer, is a model microorganism.
However, the limited gene editing methods and their defects limit the efficient genome …
However, the limited gene editing methods and their defects limit the efficient genome …
CRISPR/Cas12a Mediated Genome Editing To Introduce Amino Acid Substitutions into the Mechanosensitive Channel MscCG of Corynebacterium glutamicum
K Krumbach, CK Sonntag, L Eggeling… - ACS synthetic …, 2019 - ACS Publications
Against the background of a growing demand for the implementation of environmentally
friendly production processes, microorganisms are engineered for the large-scale …
friendly production processes, microorganisms are engineered for the large-scale …
Programming adaptive laboratory evolution of 4-hydroxyisoleucine production driven by a lysine biosensor in Corynebacterium glutamicum
X Yu, F Shi, H Liu, S Tan, Y Li - Amb Express, 2021 - Springer
Hydroxyisoleucine (4-HIL) is a promising drug for treating diabetes. In our previous study, 4-
HIL was synthesized from self-produced L-isoleucine (Ile) in Corynebacterium glutamicum …
HIL was synthesized from self-produced L-isoleucine (Ile) in Corynebacterium glutamicum …
High precision genome sequencing of engineered Gluconobacter oxydans 621H by combining long nanopore and short accurate Illumina reads
State of the art and novel high-throughput DNA sequencing technologies enable fascinating
opportunities and applications in the life sciences including microbial genomics. Short high …
opportunities and applications in the life sciences including microbial genomics. Short high …
Deletion of gene gnd encoding 6-phosphogluconate dehydrogenase promotes l-serine biosynthesis in a genetically engineered strain of Methylobacterium sp …
X Li, B Wu, K Zhou, C Jiang, P Shen - Biotechnology letters, 2019 - Springer
Objective To identify potential target genes involved in l-serine biosynthesis in
Methylobacterium sp. MB200 and to evaluate the gnd genetically-engineered strains for l …
Methylobacterium sp. MB200 and to evaluate the gnd genetically-engineered strains for l …
Metabolic Engineering of Corynebacterium glutamicum
J Becker, C Wittmann - Metabolic Engineering: Concepts and …, 2021 - Wiley Online Library
Corynebacterium glutamicum is a major workhorse in industrial biotechnology for 60 years.
As the world's flagship for amino acids, the microbe produces l‐glutamate and l‐lysine at a …
As the world's flagship for amino acids, the microbe produces l‐glutamate and l‐lysine at a …
[PDF][PDF] Novel genetic tools for production strain development of Corynebacterium glutamicum
J Hochheim - 2017 - docserv.uni-duesseldorf.de
The development of new genetic tools plays a key role in the establishment of new and/or
improved microbial production strains. Since СФЫРЗДГЕЦЗФЛЧП ЙОЧЦГПЛЕЧП belongs …
improved microbial production strains. Since СФЫРЗДГЕЦЗФЛЧП ЙОЧЦГПЛЕЧП belongs …
[PDF][PDF] Recent Advances in engineering Corynebacterium glutamicum for production of Lysine
K Divya, R Malothu, MR Dowlathabad… - Research Journal of …, 2022 - academia.edu
Lysine is an essential amino acid utilised in diverse industrial areas, mostly as animal feed
and food. It is synthesized by various organisms but the novel Corynebacterium glutamicum …
and food. It is synthesized by various organisms but the novel Corynebacterium glutamicum …