Functional roles of FGF signaling in early development of vertebrate embryos
Fibroblast growth factors (FGFs) comprise a large family of growth factors, regulating diverse
biological processes including cell proliferation, migration, and differentiation. Each FGF …
biological processes including cell proliferation, migration, and differentiation. Each FGF …
The organizer and its signaling in embryonic development
Germ layer specification and axis formation are crucial events in embryonic development.
The Spemann organizer regulates the early developmental processes by multiple regulatory …
The Spemann organizer regulates the early developmental processes by multiple regulatory …
Two Homeobox Transcription Factors, Goosecoid and Ventx1.1, Oppositely Regulate Chordin Transcription in Xenopus Gastrula Embryos
The reciprocal inhibition between two signaling centers, the Spemann organizer (dorsal
mesoderm) and ventral region (mesoderm and ectoderm), collectively regulate the overall …
mesoderm) and ventral region (mesoderm and ectoderm), collectively regulate the overall …
[HTML][HTML] Smad2 and Smad3 differentially modulate chordin transcription via direct binding on the distal elements in gastrula Xenopus embryos
Transforming growth factor (TGF) β/activin superfamily regulates diverse biological
processes including germ layer specification and axis patterning in vertebrates. TGFβ/activin …
processes including germ layer specification and axis patterning in vertebrates. TGFβ/activin …
Bmp4 Synexpression Gene, Sizzled, Transcription Is Collectively Modulated by Smad1 and Ventx1.1/Ventx2.1 in Early Xenopus Embryos
ZU Rehman, F Tayyaba, U Lee, J Kim - International Journal of Molecular …, 2022 - mdpi.com
Sizzled (Szl) is a secreted frizzled protein, having a sequence homology with the
extracellular cysteine-rich domain (CRD) of the Wnt receptor,'Frizzled'. Contrary to the other …
extracellular cysteine-rich domain (CRD) of the Wnt receptor,'Frizzled'. Contrary to the other …
Ventx family and its functional similarities with nanog: involvement in embryonic development and cancer progression
The Ventx family is one of the subfamilies of the ANTP (antennapedia) superfamily and
belongs to the NK-like (NKL) subclass. Ventx is a homeobox transcription factor and has a …
belongs to the NK-like (NKL) subclass. Ventx is a homeobox transcription factor and has a …
Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula
Inhibition of the bone morphogenetic proteins (BMPs) is the primary step toward
neuroectoderm formation in vertebrates. In this process, the Spemann organizer of the …
neuroectoderm formation in vertebrates. In this process, the Spemann organizer of the …
[HTML][HTML] Goosecoid controls neuroectoderm specification via dual circuits of direct repression and indirect stimulation in Xenopus embryos
Spemann organizer is a center of dorsal mesoderm and itself retains the mesoderm
character, but it has a stimulatory role for neighboring ectoderm cells in becoming …
character, but it has a stimulatory role for neighboring ectoderm cells in becoming …
Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos
Gastrulation is a critical step in the establishment of a basic body plan during development.
Convergence and extension (CE) cell movements organize germ layers during gastrulation …
Convergence and extension (CE) cell movements organize germ layers during gastrulation …