The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

The receptor for advanced glycation endproducts (RAGE) is an ubiquitous, transmembrane,
immunoglobulin-like receptor that exists in multiple isoforms and binds to a diverse range of …

Receptor for advanced glycation end products (RAGE) is a 45 kDa transmembrane receptor
of immunoglobulin family that can bind to various endogenous and exogenous ligands and …

High-mobility group box 1 (HMGB1) is an abundant protein in most eukaryocytes. It can bind
to several receptors such as advanced glycation end products (RAGE) and Toll-like …

The human genome codes for 21 S100 protein family members, which exhibit cell-and
tissue-specific expression patterns. Despite sharing a high degree of sequence and …

Toxoplasma gondii is a common protozoan parasite that infects up to one third of the world's
population. Notably, very little is known about innate immune sensing mechanisms for this …

Background The metastasis inducing gene MACC1 is a prognostic and predictive biomarker
for metastasis in several cancers. Its mechanism of inducing metastasis includes the …

Since its discovery in 1992, the small, 10.4 kDa calcium-binding protein S100P has gained
the attention of researchers from different scientific fields due to its potential roles in both …

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with low survival rates.
Current therapeutic treatments have very poor response rates due to the high inherent …