The ability to efficiently adapt metabolism by substrate sensing, trafficking, storage, and
utilization, dependent on availability and requirement, is known as metabolic flexibility. In …

Adipose, skeletal, and hepatic muscle tissues are the main endocrine organs that produce
adipokines, myokines, and hepatokines. These biomarkers can be harmful or beneficial to …

Background and Aims Nonalcoholic fatty liver disease (NAFLD) affects a quarter of the adult
population. A significant subset of patients are lean, but their underlying pathophysiology is …

Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

Background and aim Non-alcoholic fatty liver disease (NAFLD), affecting up to around 30%
of the world's adult population, causes considerable liver-related and extrahepatic morbidity …

Liver disease is the spectrum of liver damage ranging from simple steatosis called as
nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC). Clinically …

It is increasingly recognized that obesity is a risk factor for microvascular disease, involving
both structural and functional changes in the microvasculature. This review aims to describe …

Sarcopenic obesity (SO) is a condition characterized by the occurrence of both sarcopenia
and obesity and imposes a heavy burden on the health of the elderly. Controversies and …

Diabetes is a complex and multifactorial disease that affects millions of people worldwide,
reducing the quality of life significantly, and results in grave consequences for our health …

Introduction Obesity is a major health concern in the United States and many developed
countries. Among its many deleterious effects are those that can affect the sexual response …