The liver is a vital organ that plays a crucial role in the physiological operation of the human
body. The liver controls the body's detoxification processes as well as the storage and …

Chronic liver diseases represent a major global health problem both for their high
prevalence worldwide and, in the more advanced stages, for the limited available curative …

The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
made emerging novel coronavirus diseases (COVID-19) pandemic/endemic/or both more …

The use of tailored particle-based adjuvants constitutes a promising way to enhance antigen-
specific humoral and cellular immune responses. However, a thorough understanding of the …

Chitosan-based nanomaterials with good biodegradability, biocompatibility, and low toxicity
display immense potential as carriers for controlled delivery of various therapeutic agents …

Chitosan (Chi) is a natural biodegradable cationic polymer with remarkable potency as a
vehicle for drug or vaccine delivery. Chi possesses multiple groups, which can be used both …

Hepatitis, an inflammation of the liver parenchyma, is a viral disease. Addressing the
challenges of hepatitis is very important. Therefore, using nanoparticles (NPs) in solving the …

Among non-viral vectors, the cationic polymer chitosan has gained attention as a gene
delivery system. We hypothesized that the addition of casein into the nanoparticle's structure …

The use of particulate adjuvants offers an interesting possibility to enhance and modulate
the immune responses elicited by vaccines. Aluminium salts have been extensively used as …

Purpose The growing incidence and lethality of pancreatic cancer urges the development of
new therapeutic approaches. Anti-tumoral vaccines can potentiate the immune response …