The proteins of the BCL-2 family are key regulators of mitochondrial apoptosis, acting as
either promoters or inhibitors of cell death. The functional interplay and balance between the …

Apoptosis is a tightly regulated cell suicide program that plays an essential role in the
development and maintenance of tissue homeostasis by eliminating unnecessary or harmful …

Three families of membrane‐active peptides are commonly found in nature and are
classified according to their initial apparent activity. Antimicrobial peptides are ancient …

Bax is a pro-apoptotic protein allowing apoptosis to occur through the intrinsic, damage-
induced pathway, and amplifying that one occurring via the extrinsic, receptor mediated …

Objectives We assessed the association between acculturation and health-related quality of
life (HRQoL) among persons with a Turkish migrant background in Germany. Methods 1226 …

Cervical cancer is the second most common cause of cancer in women and has a high
mortality rate. Cisplatin, an antitumor agent, is generally used for its treatment. However, the …

The cytoplasmic membrane is one of the most frequent cell targets of antimicrobial peptides
(AMPs) and other biomolecules. Understanding the mechanism of action of AMPs at the …

UV irradiation is a major environmental factor causing skin dryness, aging and cancer. UVB
in particular triggers cumulative DNA damage, oxidative stress and mitochondrial …

Mycolactone is a lipid-like endotoxin synthesized by an environmental human pathogen,
Mycobacterium ulcerans, the causal agent of Buruli ulcer disease. Mycolactone has …

Although many cancer cells are primed for apoptosis, they usually develop resistance to cell
death at several levels. Permeabilization of the outer mitochondrial membrane, which is …