The hepatitis B virus (HBV) counts as a major global health problem, as it presents a
significant causative factor for liver-related morbidity and mortality. The development of …

Despite the existence of effective vaccines, HBV infection remains a major health problem
with 2 billion people infected worldwide. Among them, 350 million are chronically infected, a …

The purpose of this study was to identify mutations in the basic core promoter and enhancer
II region of the hepatitis B virus (HBV) that might cause the HBV e antigen (HBeAg)‐negative …

The X gene is conserved among mammalian hepadnaviruses and the X protein, pX, is
essential for viral propagation at least in the woodchuck. During the last decade, efforts have …

The hepatitis B virus X protein (HBx) sequence (154 aa) has been divided into six regions
(AF) based on its sequence homology with X proteins of other mammalian hepadnaviruses …

The hepatitis B virus (HBV) causes acute and chronic hepatitis, and the latter is a major risk
factor for the development of hepatocellular carcinoma (HCC). HBV encodes a 17-kDa …

The hepatitis B virus x protein (HBX) is expressed in HBVinfected liver cells and can interact
with a wide range of cellular proteins. In order to understand such promiscuous behavior of …

Chronic hepatitis B virus (HBV) infection has been strongly associated with hepatocellular
carcinoma (HCC) and the X protein (HBx) is thought to mediate the cellular changes …

The X protein (HBx) of the human Hepatitis B Virus (HBV) is a regulatory protein that
exercises a transcriptional activator function on a variety of regulatory elements and is …

AIM: To investigate whether the formation of aggregated HBx has a potential linking with its
cellular responses. METHODS: Recombinant HBx was expressed in Escherichia coli and …