[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy

S Shkunnikova, A Mijakovac, L Sironic, M Hanic… - Biotechnology …, 2023 - Elsevier
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Immunoglobulin G glycans–Biomarkers and molecular effectors of aging

J Krištić, G Lauc, M Pezer - Clinica chimica acta, 2022 - Elsevier
Immunoglobulin G (IgG) antibodies are post-translationally modified by the addition of
complex carbohydrate molecules–glycans, which have profound effects on the IgG function …

IgG1 glycosylation highlights premature aging in Down syndrome

BMM Streng, J Van Coillie, JG Wildenbeest… - Aging …, 2024 - Wiley Online Library
Down syndrome (DS) is characterized by lowered immune competence and premature
aging. We previously showed decreased antibody response following SARS‐CoV‐2 …

Total cell N-glycosylation is altered during neuronal differentiation of iPSC to NSC and is disturbed by trisomy 21

A Cindrić, F Vučković, A Murray, T Klarić, I Alić… - bioRxiv, 2023 - biorxiv.org
Down syndrome (DS) is a genetic condition caused by trisomy 21 (T21) and characterized
by a range of neurological symptoms including intellectual disability, early onset of …

Joint modeling of an outcome variable and integrated omics datasets using GLM-PO2PLS

Z Gu, HW Uh, J Houwing-Duistermaat… - Journal of Applied …, 2024 - Taylor & Francis
In many studies of human diseases, multiple omics datasets are measured. Typically, these
omics datasets are studied one by one with the disease, thus the relationship between …

[引用][C] IgG1 glycosylation highlights premature aging in Down syndrome

PRIDE study group - Aging Cell, 2024 - Wiley-Blackwell