Chagas cardiomyopathy: an update of current clinical knowledge and management: a scientific statement from the American Heart Association
Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally …
Chagas disease in Europe: a review for the internist in the globalized world
S Antinori, L Galimberti, R Bianco, R Grande… - European Journal of …, 2017 - Elsevier
Chagas disease (CD) or American trypanosomiasis identified in 1909 by Carlos Chagas,
has become over the last 40 years a global health concern due to the huge migration flows …
has become over the last 40 years a global health concern due to the huge migration flows …
New regimens of benznidazole monotherapy and in combination with fosravuconazole for treatment of Chagas disease (BENDITA): a phase 2, double-blind …
F Torrico, J Gascón, F Barreira, B Blum… - The Lancet Infectious …, 2021 - thelancet.com
Summary Background Current treatment for Chagas disease with the only available drugs,
benznidazole or nifurtimox, has substantial limitations, including long treatment duration and …
benznidazole or nifurtimox, has substantial limitations, including long treatment duration and …
Worldwide control and management of Chagas disease in a new era of globalization: a close look at congenital Trypanosoma cruzi infection
A Abras, C Ballart, A Fernández-Arévalo… - Clinical microbiology …, 2022 - Am Soc Microbiol
Population movements have turned Chagas disease (CD) into a global public health
problem. Despite the successful implementation of subregional initiatives to control vectorial …
problem. Despite the successful implementation of subregional initiatives to control vectorial …
Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing …
Y Carlier, J Altcheh, A Angheben, H Freilij… - PLoS neglected …, 2019 - journals.plos.org
In 2005, the World Health Organization (WHO) recognized Chagas disease (CD;
Trypanosoma cruzi infection) as a neglected tropical disease (NTD)[1] and included it into …
Trypanosoma cruzi infection) as a neglected tropical disease (NTD)[1] and included it into …
A phase 2, randomized, multicenter, placebo-controlled, proof-of-concept trial of oral fexinidazole in adults with chronic indeterminate Chagas disease
F Torrico, J Gascón, L Ortiz, J Pinto… - Clinical Infectious …, 2023 - academic.oup.com
Background Chagas disease (CD) has significant global health impact, but safe, effective
treatments remain elusive. The nitroimidazole fexinidazole is a potential treatment. Methods …
treatments remain elusive. The nitroimidazole fexinidazole is a potential treatment. Methods …
[HTML][HTML] Chagas disease research and development: Is there light at the end of the tunnel?
E Chatelain - Computational and structural biotechnology journal, 2017 - Elsevier
Chagas disease, or American trypanosomiasis, is the result of infection by the parasite
Trypanosoma cruzi. It is endemic in Latin America, and spreading around the globe due to …
Trypanosoma cruzi. It is endemic in Latin America, and spreading around the globe due to …
Chagas disease diagnostic applications: present knowledge and future steps
V Balouz, F Agüero, CA Buscaglia - Advances in parasitology, 2017 - Elsevier
Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …
illness of major significance throughout Latin America and an emergent threat to global …
Molecular diagnosis of Trypanosoma cruzi
AG Schijman - Acta tropica, 2018 - Elsevier
Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions
of people, most of them neglected populations. The different phases of the disease, the …
of people, most of them neglected populations. The different phases of the disease, the …
Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples
SA Besuschio, M Llano Murcia… - PLoS neglected …, 2017 - journals.plos.org
This study aimed to assess analytical parameters of a prototype LAMP kit that was designed
for detection of Trypanosoma cruzi DNA in human blood. The prototype is based on the …
for detection of Trypanosoma cruzi DNA in human blood. The prototype is based on the …