Myokines are muscle‐derived cytokines and chemokines that act extensively on organs and
exert beneficial metabolic functions in the whole‐body through specific signal networks …

Exercise, in the form of endurance or resistance training, leads to specific molecular and
cellular adaptions not only in skeletal muscles, but also in many other organs such as the …

In vitro and in vivo studies provide evidence that a variety of growth factors and cytokines are
actively secreted by muscle tissue. Muscle can therefore function as an endocrine and …

IL-6 is secreted from muscles to the circulation during high-intensity and long-duration
exercise, where muscle-derived IL-6 works as an energy sensor to increase release of …

Skeletal muscle extracellular matrix (ECM) is critical for muscle force production and the
regulation of important physiological processes during growth, regeneration, and …

Background: Matrix metalloproteinases (MMPs), particularly gelatinase A (MMP-2) and
gelatinase B (MMP-9), as well as their tissue inhibitors (TIMP-1 and TIMP-2), are involved in …

Aging is a complex, multifactorial process characterized by the accumulation of deleterious
effects, including biochemical adaptations of the extracellular matrix (ECM). The purpose of …

Skeletal muscle extracellular matrix remodelling has been proposed as a new feature
associated with obesity and metabolic dysfunction. Exercise training improves muscle …

We compared the effects of two ladder-based resistance training (LRT) protocols on the
skeletal muscle morphology (biceps brachialis and plantaris) of Wistar rats. Also, we …

Matrix metalloproteinase 2 (MMP‐2) is a proteolytic enzyme implicated in motility,
differentiation, and regeneration of skeletal muscle fibers through processing of extracellular …