Simple Summary Living organisms present rhythmic fluctuations every 24 h in their behavior
and metabolism to anticipate changes in the environment. These fluctuations are controlled …

Circadian clocks control the internal sleep-wake rhythmicity of 24 h which is synchronized by
the solar cycle. Circadian regulation of metabolism evolved about 2.5 billion years ago, ie …

During gestation, the developing fetus relies on precise maternal circadian signals for
optimal growth and preparation for extrauterine life. These signals regulate the daily delivery …

Chronic obstructive pulmonary disease (COPD) is a major incurable health burden, ranking
as the third leading cause of death worldwide, mainly driven by cigarette smoking. COPD is …

Cell senescence is a crucial process in cell fate determination and is involved in an
extensive array of aging-associated diseases. General perceptions and experimental …

The process of cellular senescence, which is characterized by stable cell cycle arrest, is
strongly associated with dysfunctional cellular metabolism and circadian rhythmicity, both of …

Colorectal cancer (CRC) is a growing concern all over the world. There has been a
concerted effort to identify natural bioactive compounds that can be used to prevent or …

Abstract Purpose of Review Considering the increase in life expectancy, there is a time-
related decline in biological functions. Age-related changes are also observed in the …

For decades, considerable efforts have been expended for solving the molecular
mechanisms of disease progression. An important clue to tackle this question is the …

Dormancy represents a fascinating adaptive strategy for organisms to survive in unforgiving
environments. After a period of dormancy, organisms often exhibit exceptional resilience …