Insect-specific flaviviruses: a systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization

BJ Blitvich, AE Firth - Viruses, 2015 - mdpi.com
There has been a dramatic increase in the number of insect-specific flaviviruses (ISFs)
discovered in the last decade. Historically, these viruses have generated limited interest due …

[HTML][HTML] Exploring the future of SARS-CoV-2 treatment after the first two years of the pandemic: A comparative study of alternative therapeutics

BA Babalola, OS Akinsuyi, EO Folajimi, F Olujimi… - Biomedicine & …, 2023 - Elsevier
One of the most pressing challenges associated with SARS-CoV-2 treatment is the
emergence of new variants that may be more transmissible, cause more severe disease, or …

From SARS and MERS CoVs to SARS‐CoV‐2: Moving toward more biased codon usage in viral structural and nonstructural genes

M Kandeel, A Ibrahim, M Fayez… - Journal of medical …, 2020 - Wiley Online Library
Background Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is an
emerging disease with fatal outcomes. In this study, a fundamental knowledge gap question …

Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies

AB Jena, N Kanungo, V Nayak, GBN Chainy… - Scientific reports, 2021 - nature.com
The recent outbreak of the coronavirus (SARS-CoV2) is an unprecedented threat to human
health and society across the globe. In this context, development of suitable interventions is …

Evolution of codon usage in Zika virus genomes is host and vector specific

AM Butt, I Nasrullah, R Qamar… - Emerging microbes & …, 2016 - Taylor & Francis
The codon usage patterns of viruses reflect the evolutionary changes that allow them to
optimize their survival and adapt their fitness to the external environment and, most …

Genome-wide analysis of codon usage bias in four sequenced cotton species

L Wang, H Xing, Y Yuan, X Wang, M Saeed, J Tao… - PloS one, 2018 - journals.plos.org
Codon usage bias (CUB) is an important evolutionary feature in a genome which provides
important information for studying organism evolution, gene function and exogenous gene …

Genome-wide analysis of codon usage and influencing factors in chikungunya viruses

AM Butt, I Nasrullah, Y Tong - PloS one, 2014 - journals.plos.org
Chikungunya virus (CHIKV) is an arthropod-borne virus of the family Togaviridae that is
transmitted to humans by Aedes spp. mosquitoes. Its genome comprises a 12 kb single …

Viral adaptation to host: a proteome‐based analysis of codon usage and amino acid preferences

I Bahir, M Fromer, Y Prat, M Linial - Molecular systems biology, 2009 - embopress.org
Viruses differ markedly in their specificity toward host organisms. Here, we test the level of
general sequence adaptation that viruses display toward their hosts. We compiled a …

Evolutionary basis of codon usage and nucleotide composition bias in vertebrate DNA viruses

LA Shackelton, CR Parrish, EC Holmes - Journal of molecular evolution, 2006 - Springer
Understanding the extent and causes of biases in codon usage and nucleotide composition
is essential to the study of viral evolution, particularly the interplay between viruses and host …

Analysis of preferred codon usage in the coronavirus N genes and their implications for genome evolution and vaccine design

A Sheikh, A Al-Taher, M Al-Nazawi… - Journal of virological …, 2020 - Elsevier
The nucleocapsid (N) protein of a coronavirus plays a crucial role in virus assembly and in
its RNA transcription. It is important to characterize a virus at the nucleotide level to discover …