On the evolutionary origins of obesity: a new hypothesis
D Sellayah, FR Cagampang, RD Cox - Endocrinology, 2014 - academic.oup.com
Obesity is an escalating threat of pandemic proportions, currently affecting billions of people
worldwide and exerting a devastating socioeconomic influence in industrialized countries …
worldwide and exerting a devastating socioeconomic influence in industrialized countries …
Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases
AE Pravednikova, SY Shevchenko, VV Kerchev… - Molecular …, 2020 - Springer
The hereditary aspect of obesity is a major focus of modern medical genetics. The genetic
background is known to determine a higher-than-average prevalence of obesity in certain …
background is known to determine a higher-than-average prevalence of obesity in certain …
Meta-Analysis Reveals the Association of Common Variants in the Uncoupling Protein (UCP) 1–3 Genes with Body Mass Index Variability
LA Brondani, TS Assmann, BM de Souza, AP Boucas… - PloS one, 2014 - journals.plos.org
Background The relationship between uncoupling protein (UCP) 1–3 polymorphisms and
susceptibility to obesity has been investigated in several genetic studies. However, the …
susceptibility to obesity has been investigated in several genetic studies. However, the …
Targeting mitochondrial impairment for the treatment of cardiovascular diseases: from hypertension to ischemia-reperfusion injury, searching for new pharmacological …
Mitochondria and mitochondrial proteins represent a group of promising pharmacological
target candidates in the search of new molecular targets and drugs to counteract the onset of …
target candidates in the search of new molecular targets and drugs to counteract the onset of …
Brown adipose tissue: The heat is on the heart
R Thoonen, AG Hindle… - American Journal of …, 2016 - journals.physiology.org
The study of brown adipose tissue (BAT) has gained significant scientific interest since the
discovery of functional BAT in adult humans. The thermogenic properties of BAT are well …
discovery of functional BAT in adult humans. The thermogenic properties of BAT are well …
Understanding the contemporary high obesity rate from an evolutionary genetic perspective
The topic of obesity is gaining increasing popularity globally. From an evolutionary genetic
perspective, it is believed that the main cause of the high obesity rate is the mismatch …
perspective, it is believed that the main cause of the high obesity rate is the mismatch …
The Presence of At Least Three Alleles of the ADRB3 Trp64Arg (C/T) and UCP1 −3826A/G Polymorphisms Is Associated with Protection to Overweight/Obesity and …
LA Brondani, GCK Duarte, LH Canani… - … Syndrome and Related …, 2014 - liebertpub.com
Background: We investigated whether the− 3826A/G polymorphism (rs1800592) of the
uncoupling protein 1 gene (UCP1) and the Trp64Arg polymorphism (rs4994) of the β3 …
uncoupling protein 1 gene (UCP1) and the Trp64Arg polymorphism (rs4994) of the β3 …
The relationships between leptin, genotype, and Chinese medicine body constitution for obesity
HI Hou, HY Chen, JJ Lu, SC Chang… - Evidence‐Based …, 2021 - Wiley Online Library
Background and Purpose. Obesity is a widespread and increasingly severe problem
worldwide. Several single nucleotide polymorphisms (SNPs) associated with obesity have …
worldwide. Several single nucleotide polymorphisms (SNPs) associated with obesity have …
Prevalence of uncoupling protein one genetic polymorphisms and their relationship with cardiovascular and metabolic health
Contribution of UCP1 single nucleotide polymorphisms (SNPs) to susceptibility for
cardiometabolic pathologies (CMP) and their involvement in specific risk factors for these …
cardiometabolic pathologies (CMP) and their involvement in specific risk factors for these …
Association of the UCP-1 single nucleotide polymorphism A-3826G with the dampness-phlegm pattern among Korean stroke patients
Background Patients with stroke have various syndromes and symptoms. Through pattern
identification (PI), traditional Korean medicine (TKM) classifies the several syndromes and …
identification (PI), traditional Korean medicine (TKM) classifies the several syndromes and …