Gene–disease association with human IFNL locus polymorphisms extends beyond hepatitis C virus infections
S Chinnaswamy - Genes & Immunity, 2016 - nature.com
Abstract Interferon (IFN) lambda (IFN-λ or type III IFN) gene polymorphisms were discovered
in the year 2009 to have a strong association with spontaneous and treatment-induced …
in the year 2009 to have a strong association with spontaneous and treatment-induced …
Epigenetic reprogramming around IFN1 and IFNy2 promoters in rainbow trout cells inoculated with infectious pancreatic necrosis virus (IPNV)
RA Manríquez, M Sandoval, C Loncoman… - Fish & Shellfish …, 2023 - Elsevier
Infectious pancreatic necrosis virus (IPNV) has proven to effectively evade the host antiviral
responses. This study clarifies whether the modulation of the antiviral immune response …
responses. This study clarifies whether the modulation of the antiviral immune response …
Inhibiting protein kinase D promotes airway epithelial barrier integrity in mouse models of influenza a virus infection
JM Veazey, SI Eliseeva, SE Hillman, K Stiles… - Frontiers in …, 2020 - frontiersin.org
Rationale Protein kinase D (PKD) is a serine/threonine kinase family that is involved in a
wide array of signaling pathways. Although PKD has been implicated in immune responses …
wide array of signaling pathways. Although PKD has been implicated in immune responses …
Investigation of Key Genes and Pathways in Inhibition of Oxycodone on Vincristine‐Induced Microglia Activation by Using Bioinformatics Analysis
W Liu, J Ye, H Yan - Disease Markers, 2019 - Wiley Online Library
Introduction. The neurobiological mechanisms underlying the chemotherapy‐induced
neuropathic pain are only partially understood. Among them, microglia activation was …
neuropathic pain are only partially understood. Among them, microglia activation was …
Double-stranded RNA induces cathelicidin expression in the intestinal epithelial cells through phosphatidylinositol 3-kinase-protein kinase Cζ-Sp1 pathway and …
Cathelicidin antimicrobial peptide is a key component of the host innate immune system. It is
constitutively expressed by the intestinal epithelial cells, but induced at further higher levels …
constitutively expressed by the intestinal epithelial cells, but induced at further higher levels …
Molecular characterization of yellow catfish (Pelteobagrus fulvidraco) IRF7 suggests involvement in innate immune response
X Liu, X Lv, Y Wu, J Song, X Wang, R Zhu - Developmental & Comparative …, 2020 - Elsevier
Abstract Interferon regulatory factor 7 (IRF7) serves as a critical mediator in the regulation of
type Ι interferon (IFN) response to invading pathogens. Here, an ortholog of IRF7 was …
type Ι interferon (IFN) response to invading pathogens. Here, an ortholog of IRF7 was …
Confounding by single nucleotide polymorphism rs117648444 (P70S) affects the association of interferon lambda locus variants with response to Interferon-α-ribavirin …
A Bhushan, S Ghosh, S Bhattacharjee… - Journal of Interferon & …, 2017 - liebertpub.com
Genome-wide association studies discovered interferon lambda (IFNL or IFN-λ) locus on
chromosome 19 to be involved in clearance of chronic hepatitis C virus (HCV) infection in …
chromosome 19 to be involved in clearance of chronic hepatitis C virus (HCV) infection in …
[PDF][PDF] The interactions between probiotic bacteria and respiratory viruses within the epithelium of the upper respiratory tract
T Yarlagadda - 2023 - eprints.qut.edu.au
This thesis investigated the interactions between probiotic bacteria and respiratory viruses
within the epithelium of the upper respiratory tract. Utilizing a novel 3D culture method, to …
within the epithelium of the upper respiratory tract. Utilizing a novel 3D culture method, to …
HCV 感染相关干扰素L4 真核表达载体的构建与表达
徐溪， 党引利， 吴朔 - 实用肝脏病杂志, 2018 - manu43.magtech.com.cn
目的构建HCV 感染相关干扰素IFNL4 蛋白融合His 标签的真核表达载体, 并将其在293-T
细胞中表达后进行初步纯化鉴定. 方法采用PCR 法从含人IFNL4 基因序列的质粒pFC14A-p179 …
细胞中表达后进行初步纯化鉴定. 方法采用PCR 法从含人IFNL4 基因序列的质粒pFC14A-p179 …
[PDF][PDF] 干扰素IFNL4 对巨噬细胞系THP-1 免疫应答的影响
党引利， 徐溪， 陈丽展， 张瑶， 白丹… - 现代生物医学 …, 2018 - biomed.cnjournals.com
摘要目的: 分析Interferon-lambda 4 (IFNL4) 表达与巨噬细胞免疫应答间的关系, 探讨IFNL4
调控免疫应答的信号机制, 发掘IFNL4 在免疫调理方面的潜在应用价值. 方法: 建立THP-1 …
调控免疫应答的信号机制, 发掘IFNL4 在免疫调理方面的潜在应用价值. 方法: 建立THP-1 …