Spectroscopic, thermodynamic and molecular docking studies on molecular mechanisms of drug binding to proteins

TA Wani, S Zargar, A Hussain - Molecules, 2022 - mdpi.com
Molecular recognition, which is the process of biological macromolecules interacting with
each other or various small molecules with a high specificity and affinity to form a specific …

Cu (II)-tyrosinase enzyme catalyst mediated synthesis of mosquito larvicidal active pyrazolidine-3, 5-dione derivatives with molecular docking studies and their …

V Loganathan, SK Radhakrishnan, A Ahamed… - Plos one, 2024 - journals.plos.org
The objective of this study was to develop pyrazolidine-3, 5-dione derivatives with potential
as environmentally friendly pesticides for pest control, specifically focusing on their efficacy …

Exploring the co‐activity of FDA approved drug gemcitabine and docetaxel for enhanced anti‐breast cancer activity: DFT, docking, molecular dynamics simulation and …

S Sukumaran, A Zochedh, K Chandran… - … Journal of Quantum …, 2024 - Wiley Online Library
Combining FDA‐approved medications may increase biological activity by simultaneously
targeting many protein mechanisms while being less toxic. Gemcitabine and docetaxel …

The unusual architecture of RNA-dependent RNA polymerase (RdRp)'s catalytic chamber provides a potential strategy for combination therapy against COVID-19

K Metwally, NE Abo-Dya, MI Alahmdi, MZ Albalawi… - Molecules, 2023 - mdpi.com
The unusual and interesting architecture of the catalytic chamber of the SARS-CoV-2 RNA-
dependent RNA polymerase (RdRp) was recently explored using Cryogenic Electron …

Investigating the binding of organic charge transfer co-crystals to human serum albumin by experimental and theoretical methods: spectroscopy, molecular docking …

IM Khan, A Khan, S Shakya, M Osama… - New Journal of …, 2024 - pubs.rsc.org
A new complex was formed by the transfer of charge between 2-ethylimidazole (2-EIM) as
an electron donor and 1, 2, 4, 5-benzenetetracarboxylic acid (BTC) as a π acceptor and …

Cebranopadol: An Assessment for Its Biased Activation Potential at the Mu Opioid Receptor by DFT, Molecular Docking and Molecular Dynamic Simulation Studies

M Sanam, S Ashraf, M Saeed, A Khalid… - …, 2023 - Wiley Online Library
Cocaine use disorder is a psychiatric condition affecting millions of people worldwide. Up till
now, there are no FDA approved medications reported against this disorder. Previous …

In situ carbonation mediated immobilization of arsenic oxyanions

MD Khan, YJ Song, S Shakya, C Lim, JW Ahn - Journal of Molecular …, 2023 - Elsevier
Arsenic oxyanions in water can pose severe environmental and health concerns due to
associated toxic and carcinogen characteristics. In calcareous environment, calcium …

Spectroscopic and molecular docking analysis of π-acceptor complexes with the drug barbital

AS Alamri, M Alhomrani, WF Alsanie, H Alyami… - Applied Sciences, 2022 - mdpi.com
The drug barbital (Bar) has a strong sedative–hypnotic effect. The intermolecular charge
transfer compounds associated with the chemical reactions between Bar and some π …

[HTML][HTML] Персонализированный подход к прогнозированию и профилактике галоперидол-индуцированного удлинения интервала QT: короткий обзор

РФ Насырова, АВ Кидяева, ВВ Гречкина… - Фармакогенетика и …, 2024 - cyberleninka.ru
Актуальность. Антипсихотики широко используются в психиатрии. Галоперидол
остаётся одним из наиболее часто используемым антипсихотиком в силу своей …

Impact of yohimbine on myoglobin stability: insights from molecular spectroscopic, and computational approaches

V Rupreo, J Bhattacharyya - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
The prolific role of bioactive ligands in interacting with a variety of proteins has become a
focal point of interest in pharmacokinetics and pharmacodynamics, thus sparking substantial …