Background It has been reported that diabetes mellitus affects 435 million people globally as
a primary health care problem. Despite many therapies available, many diabetes remains …

Health problems associated with aging are a major public health concern for the future.
Aging is a complex process with wide intervariability among individuals. Therefore, there is a …

Restriction of HIV-1 replication in elite controllers (ECs) is frequently attributed to T cell–
mediated immune responses, while the specific contribution of innate immune cells is less …

Background Telomere length has long been recognized as a valuable biomarker of aging
and is inversely correlated with chronological age. Various lifestyle factors have been …

With rapid increases in incidence, diverse subtypes, and complicated etiologies, kidney
disease remains a global public health problem. Iron, as an essential trace element, has …

Background: Most previous studies supported that the mammalian target of rapamycin
(mTOR) is over-activated in Alzheimer's disease (AD) and exacerbates the development of …

Objective: The mechanistic target of rapamycin (mTOR) pathway plays an integral role in
cellular metabolism, growth, and aging. While rapamycin and its analogs inhibit the mTOR …

Background The interferon‐γ (IFN‐γ) signaling pathway is activated in systemic lupus
erythematosus (SLE). This study aimed to assess the causal association between IFN‐γ, IFN …

Background The interferon-gamma (IFN-γ) signaling pathway is activated in Systemic lupus
erythematosus (SLE). This study aims to assess the causal association between IFN-γ, IFN …