Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …

Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and
one oxygen atom. The 1, 3, 4-oxadiazole and 1, 2, 4-oxadiazole have favourable physical …

Breast cancer is one of the most prevalent malignant diseases, and one of the main causes
of mortality among women across the world. Despite advances in chemotherapy, drug …

Chemotherapy is a critical treatment modality for cancer patients, but multidrug resistance
remains one of the major challenges in cancer therapy, creating an urgent need for the …

In this study, we synthesized a number of new intriguing azoles bearing nicotinoyl moiety,
their antimicrobial and antitumor activities were investigated as well. We succeeded to …

Cancer is the most lethal disease that may be found anywhere globally. Approximately 10%
of individuals die due to cancer of various types, with 19.3 million new cancer cases and 10 …

A five-membered heterocyclic compound known as 1, 2, 4-oxadiazole has one oxygen, two
carbon, and two nitrogen atoms within a ring. Numerous studies have shown that 1, 2, 4 …

The EGFR/PI3K/Akt/mTOR pathway is important for metastasis, medication resistance,
apoptosis prevention, and malignant transformation. Mutations in lung and colon cancer …

Although cancer remains the largest cause of morbidity and mortality globally, there is
growing concern about the usage of cancer drugs due to their serious side effects …

Over the past decades, pyrazole has displayed significant importance in various areas of
chemistry and industry owing to its unique nature, reactivity, and properties. Pyrazole is …