BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications
M Xing - Endocrine reviews, 2007 - academic.oup.com
In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …
received enthusiastic investigation, and significant progress has been made toward …
Heterogeneity of thyroid cancer
E Chmielik, D Rusinek, M Oczko-Wojciechowska… - Pathobiology, 2018 - karger.com
There are 5 main histological types of thyroid cancers (TCs): papillary, follicular (also known
as differentiated), poorly differentiated, anaplastic (the most aggressive form), and medullary …
as differentiated), poorly differentiated, anaplastic (the most aggressive form), and medullary …
The prevalence and prognostic value of BRAF mutation in thyroid cancer
E Kebebew, J Weng, J Bauer, G Ranvier… - Annals of …, 2007 - journals.lww.com
Objective: To examine the prevalence of BRAF mutation among thyroid cancer histologic
subtypes and determine the association of BRAF mutation with indicators of poor prognosis …
subtypes and determine the association of BRAF mutation with indicators of poor prognosis …
[HTML][HTML] Risk factors for cervical lymph node metastasis in papillary thyroid microcarcinoma: a study of 1,587 patients
X Zheng, C Peng, M Gao, J Zhi, X Hou… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
Objective The purposes of this study were to identify risk factors for cervical lymph node
metastasis and to examine the association between BRAF V600E status and clinical …
metastasis and to examine the association between BRAF V600E status and clinical …
Significance of multifocality in papillary thyroid carcinoma
JW Feng, Z Qu, AC Qin, H Pan, J Ye, Y Jiang - European Journal of …, 2020 - Elsevier
Background Although multifocality is often observed in papillary thyroid carcinoma (PTC),
the associations with clinicopathologic factors and the prognostic value are still …
the associations with clinicopathologic factors and the prognostic value are still …
[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer
F Frasca, C Nucera, G Pellegriti, P Gangemi… - Endocrine-related …, 2008 - academia.edu
Abstract BRAF (V600E) mutation is the most frequent genetic alteration in papillary thyroid
carcinomas (PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship …
carcinomas (PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship …
Multifocality, but not bilaterality, is a predictor of disease recurrence/persistence of papillary thyroid carcinoma
HJ Kim, SY Sohn, HW Jang, SW Kim… - World journal of …, 2013 - Wiley Online Library
Background Although papillary thyroid carcinoma (PTC) often presents as multifocal or
bilateral tumors, but whether multifocality or bilaterality is associated with disease …
bilateral tumors, but whether multifocality or bilaterality is associated with disease …
BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer
Abstract Background The BRAF V600E mutation is the most common genetic alteration
found in papillary thyroid cancer (PTC). Recent studies show that this mutation occurs more …
found in papillary thyroid cancer (PTC). Recent studies show that this mutation occurs more …
BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications
KT Tang, CH Lee - Journal of the chinese medical association, 2010 - journals.lww.com
Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85–
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
90% of all thyroid cancers. Genetic alternations involving the mitogen-activated protein …
Multifocal papillary thyroid cancer increases the risk of central lymph node metastasis
A Al Afif, BA Williams, MH Rigby, MJ Bullock, SM Taylor… - Thyroid, 2015 - liebertpub.com
Background: Papillary thyroid cancer (PTC) is the most common thyroid malignancy, with a
strong predilection for lymph node metastasis, most commonly to the central neck …
strong predilection for lymph node metastasis, most commonly to the central neck …