NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential

N Xie, L Zhang, W Gao, C Huang, PE Huber… - Signal transduction and …, 2020 - nature.com
Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …

Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer

AW Caliri, S Tommasi, A Besaratinia - Mutation Research/Reviews in …, 2021 - Elsevier
Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

The impact of oxidative stress in human pathology: Focus on gastrointestinal disorders

R Vona, L Pallotta, M Cappelletti, C Severi… - Antioxidants, 2021 - mdpi.com
Accumulating evidence shows that oxidative stress plays an essential role in the
pathogenesis and progression of many diseases. The imbalance between the production of …

Oxidative stress and 4‐hydroxy‐2‐nonenal (4‐HNE): Implications in the pathogenesis and treatment of aging‐related diseases

Y Li, T Zhao, J Li, M Xia, Y Li, X Wang… - Journal of …, 2022 - Wiley Online Library
Oxidative stress plays an important role in the development of aging‐related diseases by
accelerating the lipid peroxidation of polyunsaturated fatty acids in the cell membrane …

Antioxidant and anti-tumor effects of dietary vitamins A, C, and E

AJ Didier, J Stiene, L Fang, D Watkins, LD Dworkin… - Antioxidants, 2023 - mdpi.com
Oxidative stress, a condition characterized by an imbalance between pro-oxidant molecules
and antioxidant defense systems, is increasingly recognized as a key contributor to cancer …

Antioxidant therapy in cancer: rationale and progress

M Luo, L Zhou, Z Huang, B Li, EC Nice, J Xu, C Huang - Antioxidants, 2022 - mdpi.com
Cancer is characterized by increased oxidative stress, an imbalance between reactive
oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of …

Oxygen‐deficient molybdenum oxide nanosensitizers for ultrasound‐enhanced cancer metalloimmunotherapy

Y Wang, F Gong, Z Han, H Lei, Y Zhou… - Angewandte Chemie …, 2023 - Wiley Online Library
Oxygen‐deficient molybdenum oxide (MoOX) nanomaterials are prepared as novel
nanosensitizers and TME‐stimulants for ultrasound (US)‐enhanced cancer …

Anti-obesity effects of polyphenol intake: Current status and future possibilities

M Boccellino, S D'Angelo - International journal of molecular sciences, 2020 - mdpi.com
The prevalence of obesity has steadily increased worldwide over the past three decades.
The conventional approaches to prevent or treat this syndrome and its associated …

Nutraceuticals and cancer: Potential for natural polyphenols

J Maiuolo, M Gliozzi, C Carresi, V Musolino… - Nutrients, 2021 - mdpi.com
Cancer is one of the leading causes of death globally, associated with multifactorial
pathophysiological components. In particular, genetic mutations, infection or inflammation …

Oxidative stress in the brain: basic concepts and treatment strategies in stroke

M Jelinek, M Jurajda, K Duris - Antioxidants, 2021 - mdpi.com
The production of free radicals is inevitably associated with metabolism and other enzymatic
processes. Under physiological conditions, however, free radicals are effectively eliminated …