Chemical compounds derived from plants have been used since the origin of human beings
to counteract a number of diseases. Among them, the natural isoquinoline alkaloid …

Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

Numerous studies have shown that berberine and its derivatives demonstrate important anti-
tumor effects. However, the specific underlying mechanism remains unclear. Therefore …

Context• Having been used for thousands of years to treat gastrointestinal diseases, the
natural isoquinoline alkaloid, berberine, has exhibited a wide spectrum of biochemical and …

Gastrointestinal cancers are among the most prevalent cancers in the general population.
Despite effective early diagnostics and intervention, the gastrointestinal cancer‐related …

G-quadruplexes are four-stranded nucleic acid secondary structures that are formed in
guanine-rich sequences. G-quadruplexes are widely distributed in functional regions of the …

The pharmacological use of the plant alkaloid berberine is based on its antibacterial and
anti‐inflammatory properties; recently, anticancer activity has been attributed to this …

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, highly metastatic malignancy
and accounts for 85% of pancreatic cancers. PDAC patients have poor prognosis with a five …

A herbal alkaloid Berberine (Ber), used for centuries in Ayurvedic, Chinese, Middle-Eastern,
and native American folk medicines, is nowadays proved to function as a safe anticancer …

Berberine (BBR) is a common nutraceutical consumed by millions worldwide. BBR has
many different effects on human health, eg, diabetes, diarrhea, inflammation and now more …