[HTML][HTML] Current evidence on the bioavailability of food bioactive peptides
L Amigo, B Hernández-Ledesma - Molecules, 2020 - mdpi.com
Food protein-derived bioactive peptides are recognized as valuable ingredients of functional
foods and/or nutraceuticals to promote health and reduce the risk of chronic diseases …
foods and/or nutraceuticals to promote health and reduce the risk of chronic diseases …
[HTML][HTML] New insights into the role of seed oil body proteins in metabolism and plant development
Oil bodies (OBs) are ubiquitous dynamic organelles found in plant seeds. They have
attracted increasing attention recently because of their important roles in plant physiology …
attracted increasing attention recently because of their important roles in plant physiology …
N-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex
Although many eukaryotic proteins are amino (N)–terminally acetylated, structural
mechanisms by which N-terminal acetylation mediates protein interactions are largely …
mechanisms by which N-terminal acetylation mediates protein interactions are largely …
Targeted therapeutic delivery using engineered exosomes and its applications in cardiovascular diseases
D Xitong, Z Xiaorong - Gene, 2016 - Elsevier
Exosomes are 30–120 nm membrane bound vesicles secreted naturally by almost all cells
and exist in all body fluids. Accumulating evidence has shown that exosomes contain …
and exist in all body fluids. Accumulating evidence has shown that exosomes contain …
N‐terminal methionine processing
PT Wingfield - Current protocols in protein science, 2017 - Wiley Online Library
Protein synthesis is initiated by methionine in eukaryotes and by formylmethionine in
prokaryotes. N‐terminal methionine can be co‐translationally cleaved by the enzyme …
prokaryotes. N‐terminal methionine can be co‐translationally cleaved by the enzyme …
[HTML][HTML] The N-terminal methionine of cellular proteins as a degradation signal
HK Kim, RR Kim, JH Oh, H Cho, A Varshavsky… - Cell, 2014 - cell.com
The Arg/N-end rule pathway targets for degradation proteins that bear specific unacetylated
N-terminal residues while the Ac/N-end rule pathway targets proteins through their N α …
N-terminal residues while the Ac/N-end rule pathway targets proteins through their N α …
The N-end rule pathway: emerging functions and molecular principles of substrate recognition
SM Sriram, BY Kim, YT Kwon - Nature reviews Molecular cell biology, 2011 - nature.com
The N-end rule defines the protein-destabilizing activity of a given amino-terminal residue
and its post-translational modification. Since its discovery 25 years ago, the pathway …
and its post-translational modification. Since its discovery 25 years ago, the pathway …
The eukaryotic N-end rule pathway: conserved mechanisms and diverse functions
The N-end rule pathway of targeted proteolysis, which relates the stability of a protein to the
nature of its N-terminus, has emerged as a key regulator of diverse processes in eukaryotes …
nature of its N-terminus, has emerged as a key regulator of diverse processes in eukaryotes …
Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway
SE Park, JM Kim, OH Seok, H Cho, B Wadas, SY Kim… - Science, 2015 - science.org
Rgs2, a regulator of G proteins, lowers blood pressure by decreasing signaling through Gαq.
Human patients expressing Met-Leu-Rgs2 (ML-Rgs2) or Met-Arg-Rgs2 (MR-Rgs2) are …
Human patients expressing Met-Leu-Rgs2 (ML-Rgs2) or Met-Arg-Rgs2 (MR-Rgs2) are …
N‐terminal acetylation of α‐synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer
L Kang, GM Moriarty, LA Woods, AE Ashcroft… - Protein …, 2012 - Wiley Online Library
The conformational properties of soluble α‐synuclein, the primary protein found in patients
with Parkinson's disease, are thought to play a key role in the structural transition to amyloid …
with Parkinson's disease, are thought to play a key role in the structural transition to amyloid …