Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis

DP Robinson, SL Klein - Hormones and behavior, 2012 - Elsevier
This article is part of a Special Issue “Neuroendocrine-Immune Axis in Health and Disease.”
During pregnancy, it is evolutionarily advantageous for inflammatory immune responses that …

Consensus recommendations for the diagnosis and treatment of multiple sclerosis: 2019 revisions to the MENACTRIMS guidelines

B Yamout, M Sahraian, S Bohlega, M Al-Jumah… - Multiple sclerosis and …, 2020 - Elsevier
With evolving diagnostic criteria and the advent of new oral and parenteral therapies for MS,
most current diagnostic and treatment algorithms need revision and updating. The diagnosis …

[HTML][HTML] Evaluation of pregnancy outcomes from the Tysabri®(natalizumab) pregnancy exposure registry: a global, observational, follow-up study

S Friend, S Richman, G Bloomgren, LM Cristiano… - BMC neurology, 2016 - Springer
Background Patients with multiple sclerosis (MS) or Crohn's disease (CD) being treated with
natalizumab (Tysabri®, Biogen) who are planning to become pregnant or discover they are …

[HTML][HTML] Changes in T cell and dendritic cell phenotype from mid to late pregnancy are indicative of a shift from immune tolerance to immune activation

NM Shah, AA Herasimtschuk, A Boasso… - Frontiers in …, 2017 - frontiersin.org
During pregnancy, the mother allows the immunologically distinct fetoplacental unit to
develop and grow. Opinions are divided as to whether this represents a state of fetal-specific …

[HTML][HTML] An integrated metabolomics approach for the research of new cerebrospinal fluid biomarkers of multiple sclerosis

D Pieragostino, M D'Alessandro, M di Ioia… - Molecular …, 2015 - pubs.rsc.org
Multiple Sclerosis (MuS) is a disease caused due to an autoimmune attack against myelin
components in which non proteic mediators may play a role. Recent research in …

Exacerbations of autoimmune diseases during pregnancy and postpartum

VV Borba, G Zandman-Goddard, Y Shoenfeld - Best Practice & Research …, 2019 - Elsevier
Autoimmune diseases represent a complex heterogeneous group of disorders that occur as
a results of immune homeostasis dysregulation and loss of self-tolerance. Interestingly, more …

Pregnancy and the use of disease‐modifying therapies in patients with multiple sclerosis: benefits versus risks

R Alroughani, A Altintas, M Al Jumah… - Multiple sclerosis …, 2016 - Wiley Online Library
The burden of multiple sclerosis (MS) in women of childbearing potential is increasing, with
peak incidence around the age of 30 years, increasing incidence and prevalence, and …

Reproduction and the risk of multiple sclerosis

M Magyari, N Koch-Henriksen… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: The incidence of multiple sclerosis (MS) in Denmark has doubled in women
since 1970, whereas it has been almost unchanged in men. Objectives: To investigate …

Therapeutic plasma exchange and pregnancy: A case report and guidelines for performing plasma exchange in a pregnant patient

JL Cox, SA Koepsell… - Journal of clinical …, 2017 - Wiley Online Library
Therapeutic plasma exchange (TPE) has been demonstrated to be of significant clinical
value in a number of diseases and conditions, with well‐established guidelines and …

Safety of disease-modifying drugs for multiple sclerosis in pregnancy: current challenges and future considerations for effective pharmacovigilance

E Lu, BW Wang, C Guimond, A Synnes… - Expert Review of …, 2013 - Taylor & Francis
When contemplating a pregnancy, women treated for multiple sclerosis (MS) with a disease-
modifying drug must decide to discontinue their medication before conception or risk …