[PDF][PDF] Neural mechanisms of binaural processing in the auditory brainstem

TCT Yin, PH Smith, PX Joris - Compr Physiol, 2019 - researchgate.net
Spatial hearing, and more specifically the ability to localize sounds in space, is one of the
most studied and best understood aspects of hearing. Because there is no coding of …

Synaptic integration in dendrites: exceptional need for speed

NL Golding, D Oertel - The Journal of physiology, 2012 - Wiley Online Library
Some neurons in the mammalian auditory system are able to detect and report the
coincident firing of inputs with remarkable temporal precision. A strong, low‐voltage …

Precisely timed inhibition facilitates action potential firing for spatial coding in the auditory brainstem

B Beiderbeck, MH Myoga, NIC Müller… - Nature …, 2018 - nature.com
The integration of excitatory and inhibitory synaptic inputs is fundamental to neuronal
processing. In the mammalian auditory brainstem, neurons compare excitatory and …

A mechanistic understanding of the role of feedforward inhibition in the mammalian sound localization circuitry

MT Roberts, SC Seeman, NL Golding - Neuron, 2013 - cell.com
Feedforward inhibition sharpens the precision of neurons throughout ascending auditory
pathways, including the binaural neurons of the medial superior olive (MSO). However, the …

Differential recruitment of dentate gyrus interneuron types by commissural versus perforant pathways

TT Hsu, CT Lee, MH Tai, CC Lien - Cerebral cortex, 2016 - academic.oup.com
Gamma-aminobutyric acidergic (GABAergic) interneurons (INs) in the dentate gyrus (DG)
provide inhibitory control to granule cell (GC) activity and thus gate incoming signals to the …

Principal cells of the brainstem's interaural sound level detector are temporal differentiators rather than integrators

TP Franken, PX Joris, PH Smith - Elife, 2018 - elifesciences.org
The brainstem's lateral superior olive (LSO) is thought to be crucial for localizing high-
frequency sounds by coding interaural sound level differences (ILD). Its neurons weigh …

Directional hearing by linear summation of binaural inputs at the medial superior olive

M van der Heijden, JAM Lorteije, A Plauška… - Neuron, 2013 - cell.com
Neurons in the medial superior olive (MSO) enable sound localization by their remarkable
sensitivity to submillisecond interaural time differences (ITDs). Each MSO neuron has its …

Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus

S Li, BI Kalappa, T Tzounopoulos - Elife, 2015 - elifesciences.org
Vulnerability to noise-induced tinnitus is associated with increased spontaneous firing rate
in dorsal cochlear nucleus principal neurons, fusiform cells. This hyperactivity is caused, at …

Subthreshold resonance properties contribute to the efficient coding of auditory spatial cues

MWH Remme, R Donato… - Proceedings of the …, 2014 - National Acad Sciences
Neurons in the medial superior olive (MSO) and lateral superior olive (LSO) of the auditory
brainstem code for sound-source location in the horizontal plane, extracting interaural time …

Synaptic plasticity in the auditory system: a review

E Friauf, AU Fischer, MF Fuhr - Cell and tissue research, 2015 - Springer
Synaptic transmission via chemical synapses is dynamic, ie, the strength of postsynaptic
responses may change considerably in response to repeated synaptic activation. Synaptic …