One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

The microbiota-gut-brain axis or simple gut-brain axis (GBA) is a complex and interactive
bidirectional communication network linking the gut to the brain. Alterations in the …

Background The intestinal microbiota plays an important role in regulating gastrointestinal
(GI) physiology in part through interactions with the enteric nervous system (ENS) …

Glial cells have been proposed as a source of neural progenitors, but the mechanisms
underpinning the neurogenic potential of adult glia are not known. Using single cell …

The enteric nervous system (ENS) of the gastrointestinal (GI) tract interacts with the local
immune system bidirectionally. Recent publications have demonstrated that such …

Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …

Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the
“support” cells of the enteric nervous system, studies over the past 20 years have unveiled a …

Enteric glial cells (EGC) modulate motility, maintain gut homeostasis, and contribute to
neuroinflammation in intestinal diseases and motility disorders. Damage induces a reactive …

The gastrointestinal tract is innervated by the enteric nervous system (ENS), a complex
network of neurons and glial cells, also called the “second brain”. Enteric glial cells, one of …

Here, we establish that plasticity exists within the postnatal enteric nervous system by
demonstrating the reinnervation potential of post-mitotic enteric neurons (ENs). Employing …