Non-coding RNAs in polycystic ovary syndrome: a systematic review and meta-analysis

L Mu, X Sun, M Tu, D Zhang - Reproductive Biology and Endocrinology, 2021 - Springer
Background Genetic, environmental and epigenetical factors may play important roles in the
pathogenesis of polycystic ovary syndrome (PCOS), however the etiology of PCOS remains …

miRNAs as a novel clinical biomarker and therapeutic targets in polycystic ovary syndrome (PCOS): a review

M Abdalla, H Deshmukh, SL Atkin, T Sathyapalan - Life Sciences, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder in females of
the reproductive age. PCOS is commonly manifested as ovulatory dysfunction, clinical and …

Exosomal micro RNA s as tumor markers in epithelial ovarian cancer

C Pan, I Stevic, V Müller, Q Ni… - Molecular …, 2018 - Wiley Online Library
Specific micro RNA s (mi RNA s) are packaged in exosomes that regulate processes in
tumor development and progression. The current study focuses on the influence of …

[PDF][PDF] Retracted: lncRNA PVT1/microRNA-17-5p/PTEN axis regulates secretion of E2 and P4, proliferation, and apoptosis of ovarian granulosa cells in PCOS

G Liu, S Liu, G Xing, F Wang - Molecular Therapy-Nucleic Acids, 2020 - cell.com
Recently, the roles of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) were
identified in polycystic ovary syndrome (PCOS). In the present study, we investigated the …

The Translational Role of miRNA in Polycystic Ovary Syndrome: From Bench to Bedside—A Systematic Literature Review

SG Vitale, AM Fulghesu, M Mikuš, R Watrowski… - Biomedicines, 2022 - mdpi.com
MicroRNAs (miRNAs) are small, non-coding RNAs that are essential for the regulation of
post-transcriptional gene expression during tissue development and differentiation. They are …

MicroRNAs: tiny molecules with a significant role in mammalian follicular and oocyte development

D Tesfaye, S Gebremedhn, D Salilew-Wondim… - …, 2018 - rep.bioscientifica.com
The genetic regulation of female fertility (follicular development, oocyte maturation and early
preimplantation embryo development) involves the spatio-temporal regulation of those …

Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome

S Risal, C Li, Q Luo, R Fornes, H Lu, G Eriksson… - Cell Reports …, 2023 - cell.com
The transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female
progeny are being revealed. As there is evidence that a male equivalent of PCOS may …

Therapeutic potential of exosomes/miRNAs in polycystic ovary syndrome induced by the alteration of circadian rhythms

W Chen, Q Huang, Z Wang, X Zhuang, S Lin… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a reproductive dysfunction associated with endocrine
disorders and is most common in women of reproductive age. Clinical and/or biochemical …

MicroRNA-mediated gene regulatory mechanisms in mammalian female reproductive health

S Gebremedhn, A Ali, M Hossain, M Hoelker… - International journal of …, 2021 - mdpi.com
Mammalian reproductive health affects the entire reproductive cycle starting with the ovarian
function through implantation and fetal growth. Various environmental and physiological …

Implicating androgen excess in propagating metabolic disease in polycystic ovary syndrome

P Kempegowda, E Melson… - Therapeutic …, 2020 - journals.sagepub.com
Polycystic ovary syndrome (PCOS) has been traditionally perceived as a reproductive
disorder due to its most common presentation with menstrual dysfunction and infertility …