Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …

Melatonin, through its different receptors, has pleiotropic functions in mammalian brain.
Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated …

Cluster headache is a debilitating primary headache disorder that affects approximately
0.1% of the population worldwide. Cluster headache attacks involve severe unilateral pain …

The involvement of melatonin in mammalian brain pathophysiology has received growing
interest, but information about the anatomical distribution of its two G‐protein‐coupled …

Background: Melatonin (MLT) is a pleiotropic neurohormone controlling many physiological
processes and whose dysfunction may contribute to several different diseases, such as …

A growing body of evidence supports the modulation of pain by light exposure. As such,
phototherapy is being increasingly utilized for the management of a variety of pain …

We previously suggested that women with endometriosis have increased oxidative stress in
the peritoneal cavity. To assess whether antioxidant supplementation would ameliorate …

Melatonin possesses sedative, hypnotic, analgesic, antiinflammatory, antioxidative, and
chronobiotic properties that distinguish it as an attractive alternative premedicant. A …

The intensity of pain sensation exhibits marked day and night variations. Since the intensity
of pain perception is low during dark hours of the night when melatonin levels are high, this …