[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

Diet and depression: exploring the biological mechanisms of action

W Marx, M Lane, M Hockey, H Aslam, M Berk… - Molecular …, 2021 - nature.com
The field of nutritional psychiatry has generated observational and efficacy data supporting a
role for healthy dietary patterns in depression onset and symptom management. To guide …

Evidences for adult hippocampal neurogenesis in humans

EP Moreno-Jiménez, J Terreros-Roncal… - Journal of …, 2021 - Soc Neuroscience
The rodent hippocampus generates new neurons throughout life. This process, named adult
hippocampal neurogenesis (AHN), is a striking form of neural plasticity that occurs in the …

Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

RB Price, R Duman - Molecular psychiatry, 2020 - nature.com
Chronic stress and depressive-like behaviors in basic neuroscience research have been
associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss …

Formation and integration of new neurons in the adult hippocampus

A Denoth-Lippuner, S Jessberger - Nature Reviews Neuroscience, 2021 - nature.com
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian brain.
Adult-born neurons shape brain function, and endogenous NSCs could potentially be …

Physical activity for cognitive health promotion: an overview of the underlying neurobiological mechanisms

C Chen, S Nakagawa - Ageing research reviews, 2023 - Elsevier
Physical activity is one of the modifiable factors of cognitive decline and dementia with the
strongest evidence. Although many influential reviews have illustrated the neurobiological …

Early life adversity shapes neural circuit function during sensitive postnatal developmental periods

L Malave, MT van Dijk, C Anacker - Translational psychiatry, 2022 - nature.com
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

C Anacker, VM Luna, GS Stevens, A Millette, R Shores… - Nature, 2018 - nature.com
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by
environmental influences, and functionally implicated in behavioural responses to stress …

Sex differences in depression: Insights from clinical and preclinical studies

RS Eid, AR Gobinath, LAM Galea - Progress in neurobiology, 2019 - Elsevier
Depression represents a global mental health concern, and disproportionally affects women
as they are twice more likely to be diagnosed than men. In this review, we provide a …

Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …