Inducible nitric oxide synthase: Regulation, structure, and inhibition
MA Cinelli, HT Do, GP Miley… - Medicinal research …, 2020 - Wiley Online Library
A considerable number of human diseases have an inflammatory component, and a key
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …
Nitric oxide production in plants: an update
J Astier, I Gross, J Durner - Journal of Experimental Botany, 2018 - academic.oup.com
Nitric oxide (NO) is a key signaling molecule in plant physiology. However, its production in
photosynthetic organisms remains partially unresolved. The best characterized NO …
photosynthetic organisms remains partially unresolved. The best characterized NO …
Synergistic effects of nitric oxide and silicon on promoting plant growth, oxidative stress tolerance and reduction of arsenic uptake in Brassica juncea
Arsenic (As) polluted food chain has become a serious issue for the growth and
development of humans, animals and plants. Nitric oxide (NO) or silicon (Si) may mitigate As …
development of humans, animals and plants. Nitric oxide (NO) or silicon (Si) may mitigate As …
Inflammation and lymphatic function
S Schwager, M Detmar - Frontiers in immunology, 2019 - frontiersin.org
The lymphatic vasculature plays a crucial role in regulating the inflammatory response by
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …
influencing drainage of extravasated fluid, inflammatory mediators, and leukocytes …
Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: possible therapeutic targets?
L Rochette, J Lorin, M Zeller, JC Guilland… - Pharmacology & …, 2013 - Elsevier
Nitric oxide (radical dot NO) is synthetized enzymatically from l-arginine (l-Arg) by three NO
synthase isoforms, iNOS, eNOS and nNOS. The synthesis of NO is selectively inhibited by …
synthase isoforms, iNOS, eNOS and nNOS. The synthesis of NO is selectively inhibited by …
Decline in nitrosative stress drives antibiotic persister regrowth during infection
Internalization of pathogenic bacteria by macrophages results in formation of antibiotic-
tolerant persisters. These cells are maintained in a non-growing state for extended periods …
tolerant persisters. These cells are maintained in a non-growing state for extended periods …
Role of nitric oxide in neurodegeneration: function, regulation, and inhibition
Reactive nitrogen species (RNS) and reactive oxygen species (ROS), collectively known as
reactive oxygen and nitrogen species (RONS), are the products of normal cellular …
reactive oxygen and nitrogen species (RONS), are the products of normal cellular …
Redox activation of Nrf2 & NF-κB: a double end sword?
M Buelna-Chontal, C Zazueta - Cellular signalling, 2013 - Elsevier
Moderate concentrations of reactive oxygen species (ROS) are produced by diverse sources
under physiological conditions. At such low levels, these molecules may act as upstream …
under physiological conditions. At such low levels, these molecules may act as upstream …
Accurate diagnosis of hepatic fibrosis with dual detection of nitric oxide and viscosity by a ratiometric fluorescent probe
S Han, L Yang, M Liu, H Li, X Song - Chemical Engineering Journal, 2023 - Elsevier
Hepatic fibrosis (HF) is a prevalent and irreversible liver disease caused by unhealthy
lifestyles. However, no specific diagnosis tools, except for liver biopsy, are available for HF …
lifestyles. However, no specific diagnosis tools, except for liver biopsy, are available for HF …
Inducible nitric oxide synthase inhibitors: A comprehensive update
Inducible nitric oxide synthase (iNOS), which is expressed in response to bacterial/
proinflammatory stimuli, generates nitric oxide (NO) that provides cytoprotection …
proinflammatory stimuli, generates nitric oxide (NO) that provides cytoprotection …