[HTML][HTML] Clinical-pathologic challenges in the classification of pulmonary neuroendocrine neoplasms and targets on the horizon for future clinical practice

JL Derks, N Rijnsburger, BCM Hermans… - Journal of Thoracic …, 2021 - Elsevier
Diagnosing a pulmonary neuroendocrine neoplasm (NEN) may be difficult, challenging
clinical decision making. In this review key clinical and pathological issues and informative …

Lung carcinoids: A comprehensive review for clinicians

D Granberg, CC Juhlin, H Falhammar, E Hedayati - Cancers, 2023 - mdpi.com
Simple Summary Lung carcinoids are divided into typical and atypical. Most tumors are slow-
growing yet have malignant potential, which is more common in patients harboring atypical …

[HTML][HTML] Atypical carcinoid tumor of the lung: a surveillance, epidemiology, and end results database analysis

CE Steuer, M Behera, S Kim, Z Chen, NF Saba… - Journal of Thoracic …, 2015 - Elsevier
Background Atypical carcinoid (AC) of the lung is a rare form of thoracic malignancy. The
limited knowledge of its biology and outcome stems largely from small, single institution …

Recent advances in the management of typical and atypical lung carcinoids

N Prinzi, RE Rossi, C Proto, G Leuzzi, A Raimondi… - Clinical Lung Cancer, 2021 - Elsevier
Neuroendocrine neoplasms of the lung represent about 20% to 30% of all neuroendocrine
tumors. On the basis of clinical and pathologic characteristics, 2 different categories of …

Orthopedia homeobox (OTP) in pulmonary neuroendocrine tumors: the diagnostic value and possible molecular interactions

L Moonen, J Derks, AM Dingemans, EJ Speel - Cancers, 2019 - mdpi.com
Generally, patients with stage I-IIIa (TNM) pulmonary carcinoid disease have a favourable
prognosis after curative resection. Yet, distant recurrence of disease after curative surgery …

Classification of lung neuroendocrine tumors: lights and shadows

M Volante, G Gatti, M Papotti - Endocrine, 2015 - Springer
Neuroendocrine tumors of the lung are classified into low-grade typical and intermediate-
grade atypical carcinoids, and high-grade poorly differentiated neuroendocrine carcinomas …

Challenges in the diagnosis and management of well-differentiated neuroendocrine tumors of the lung (typical and atypical carcinoid): current status and future …

EM Wolin - The Oncologist, 2015 - academic.oup.com
Neuroendocrine tumors (NET) of the lung represent approximately 25% of all primary lung
tumors and can be classified as low grade (typical carcinoids), intermediate grade (atypical …

Surgical resection for pulmonary carcinoid: long-term results of multicentric study—the importance of pathological N status, more than we thought

G Cusumano, L Fournel, S Strano, D Damotte… - Lung, 2017 - Springer
Background Histological subdivision into typical (TC) and atypical (AC) is crucial for
treatment and prognosis of lung carcinoids but can be also very challenging, even for …

[HTML][HTML] Improvement in TNM staging of pulmonary neuroendocrine tumors requires histology and regrouping of tumor size

M Cattoni, E Vallières, LM Brown, AA Sarkeshik… - The Journal of thoracic …, 2018 - Elsevier
Objective Neuroendocrine tumors of the lung are currently staged with the 7th edition TNM
non–small cell lung cancer staging system. This decision, based on data analysis without …

Pulmonary neuroendocrine tumors

AC Borczuk - Surgical pathology clinics, 2020 - Elsevier
Pulmonary neuroendocrine tumors represent a morphologic spectrum of tumors from the
well-differentiated typical carcinoid tumor, to the intermediate-grade atypical carcinoid tumor …