[HTML][HTML] Bioprospecting of endophytes in medicinal plants of Thar Desert: An attractive resource for biopharmaceuticals

G Yadav, M Meena - Biotechnology Reports, 2021 - Elsevier
Endophytes live asymptomatically within the healthy tissues of plant parts of the host, has
grabbed the attention of ecologists, chemists, and researchers to have a broad spectral of …

Exploring current scenario and developments in the field of microbial L-asparaginase production and applications: A review

PG Patel, HZ Panseriya, AK Vala, BP Dave… - Process …, 2022 - Elsevier
L-asparaginase, an amidohydrolase that catalyses break down of L-asparagine into aspartic
acid and ammonia, is one of the most prominent biopharmaceuticals. L-asparaginase (LA) …

Promising inhibitors of main protease of novel corona virus to prevent the spread of COVID-19 using docking and molecular dynamics simulation

D Kumar, K Kumari, VK Vishvakarma… - Journal of …, 2021 - Taylor & Francis
Abstract Coronavirus disease-2019 (COVID-19) is a global health emergency and the matter
of serious concern, which has been declared a pandemic by WHO. Till date, no potential …

Polyurethane degradation by extracellular urethanase producing bacterial isolate Moraxella catarrhalis strain BMPPS3

B Maheswaran, JS Raj, P Pandiyarajan, RJ Santhi… - Environmental …, 2024 - Elsevier
Plastic waste has become a global issue and a threat to the ecosystem. The present study
isolated polyurethane (PU) degrading bacterial species from soil dumped with plastic …

Molecular cloning, structural modeling and characterization of a novel glutaminase-free L-asparaginase from Cobetia amphilecti AMI6

MG Farahat, D Amr, A Galal - International journal of biological …, 2020 - Elsevier
The exploration of new sources of L-asparaginase with low glutaminase activity is of great
interest in both medical and food applications. In the current study, a novel L-asparaginase …

Harnessing bacterial endophytes for environmental resilience and agricultural sustainability

M Muhammad, A Wahab, A Waheed… - Journal of …, 2024 - Elsevier
In the current era of environmental disasters and the necessity of sustainable development,
bacterial endophytes have gotten attention for their role in improving agricultural productivity …

Endophytic fungi as a promising source of anticancer l-asparaginase: a review

J Parashiva, BR Nuthan, D Rakshith, S Satish - Current Microbiology, 2023 - Springer
L-asparaginase is a tetrameric enzyme from the amidohydrolases family, that catalyzes the
breakdown of L-asparagine into L-aspartic acid and ammonia. Since its discovery as an …

Characterization, Anti-proliferative Activity, and Bench-Scale Production of Novel pH-Stable and Thermotolerant L-Asparaginase from Bacillus licheniformis PPD37

P Patel, A Patel, R Agarwal-Rajput, R Rawal… - Applied Biochemistry …, 2023 - Springer
Bacterial L-asparaginase (LA) is a chemotherapeutic drug that has remained mainstay of
cancer treatment for several decades. LA has been extensively used worldwide for the …

Recombinant l-Asparaginase II from Lactobacillus casei subsp. casei ATCC 393 and Its Anticancer Activity

SS Aishwarya, E Selvarajan, S Iyappan… - Indian journal of …, 2019 - Springer
Abstract l-asparaginases from bacterial origin are employed extensively in leukemic
treatment and food industry. The present study focuses on the characterization of the …

Engineering and expression strategies for optimization of L-Asparaginase development and production

AN Shishparenok, YA Gladilina… - International Journal of …, 2023 - mdpi.com
Genetic engineering for heterologous expression has advanced in recent years. Model
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …