Nutrition in adolescent growth and development

SA Norris, EA Frongillo, MM Black, Y Dong, C Fall… - The lancet, 2022 - thelancet.com
During adolescence, growth and development are transformative and have profound
consequences on an individual's health in later life, as well as the health of any potential …

Influenza virus and SARS-CoV-2: pathogenesis and host responses in the respiratory tract

T Flerlage, DF Boyd, V Meliopoulos… - Nature Reviews …, 2021 - nature.com
Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …

Androgen receptor activity in T cells limits checkpoint blockade efficacy

X Guan, F Polesso, C Wang, A Sehrawat, RM Hawkins… - Nature, 2022 - nature.com
Immune checkpoint blockade has revolutionized the field of oncology, inducing durable anti-
tumour immunity in solid tumours. In patients with advanced prostate cancer …

Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission

H Peckham, NM de Gruijter, C Raine… - Nature …, 2020 - nature.com
Anecdotal evidence suggests that Coronavirus disease 2019 (COVID-19), caused by the
coronavirus SARS-CoV-2, exhibits differences in morbidity and mortality between sexes …

Sex disparities matter in cancer development and therapy

S Haupt, F Caramia, SL Klein, JB Rubin… - Nature Reviews …, 2021 - nature.com
Curing cancer through precision medicine is the paramount aim of the new wave of
molecular and genomic therapies. Currently, whether patients with non-reproductive …

Natural killer cell dysfunction and its role in COVID-19

C van Eeden, L Khan, MS Osman… - International journal of …, 2020 - mdpi.com
When facing an acute viral infection, our immune systems need to function with finite
precision to enable the elimination of the pathogen, whilst protecting our bodies from …

Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice

Z Zhang, X Tian, JY Lu, K Boit, J Ablaeva, FT Zakusilo… - Nature, 2023 - nature.com
Abundant high-molecular-mass hyaluronic acid (HMM-HA) contributes to cancer resistance
and possibly to the longevity of the longest-lived rodent—the naked mole-rat,. To study …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

[HTML][HTML] Sex differences in markers of oxidation and inflammation. Implications for ageing

IM de Toda, M González-Sánchez… - Mechanisms of ageing …, 2023 - Elsevier
Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …

Age and sex-associated changes of complement activity and complement levels in a healthy Caucasian population

M Gaya da Costa, F Poppelaars, C Van Kooten… - Frontiers in …, 2018 - frontiersin.org
Introduction: The complement system is essential for an adequate immune response. Much
attention has been given to the role of complement in disease. However, to better …