Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

Drug nanocrystals are a versatile option for drug delivery purposes, and while the number of
poorly soluble drug materials is all the time increasing, more research in this area is …

Microneedles (MNs) technology has many advantages and is an ideal local transdermal
drug delivery method. Here we synthesized photocrosslinkable dextran methacrylate …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

A two-tier approach has been proposed for targeted and synergistic combination therapy
against metastatic breast cancer. First, it comprises the development of a paclitaxel (PX) …

HR+/HER2–metastatic breast cancer (MBC) is one of the most common and life-threatening
conditions diagnosed in women. The endocrine therapy using an orally active CDK4/6 …

Paclitaxel (PTX) is a chemotherapeutic agent that belongs to the taxane family and which
was approved to treat various kinds of cancers including breast cancer, ovarian cancer …

Drug nanocrystals, which are comprised of active pharmaceutical ingredients and only a
small amount of essential stabilizers, have the ability to improve the solubility, dissolution …

In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …

Triple negative breast cancer (TNBC) is the most dangerous subtype of breast cancer
accompanying by unfavorable prognosis due to lack of specific therapeutic targets …