Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

The transient receptor potential (TRP) superfamily consists of a large number of
nonselective cation channels with variable degree of Ca2+-permeability. The 28 mammalian …

The transient receptor potential channel TRPM7 is a master regulator of the organismal
balance of divalent cations that plays an essential role in embryonic development, immune …

The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a
heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac …

The sinus node is a collection of highly specialised cells constituting the heart's pacemaker.
The molecular underpinnings of its pacemaking abilities are debated. Using high-resolution …

The transient receptor potential ion channel subfamily M, member 7 (TRPM7), is a
ubiquitously expressed protein that is required for mouse embryonic development. TRPM7 …

Transient receptor potential (TRP) channels are nonselective cationic channels that are
generally Ca2+ permeable and have a heterogeneous expression in the heart. In the …

Cardiac fibroblasts (CF) play a pivotal role in preserving myocardial function and integrity of
the heart tissue after injury, but also contribute to future susceptibility to heart failure. CF …

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed membrane protein consisting of ion channel and protein kinase domains. TRPM7 …

Osteoarthritis (OA) is a progressive degenerative disease of articular cartilage and
surrounding tissues, and is associated with both advanced age and joint injury …