The employment of liquid chromatography‐mass spectrometry (LC‐MS) untargeted and
targeted metabolomics has led to the discovery of novel biomarkers and improved the …

Derivatization, or chemical structure modification, is often used in bioanalysis performed by
liquid chromatography technique in order to enhance detectability or to improve the …

Microextraction techniques have attracted the attention of many researchers working in the
field of bioanalysis due to their unique advantages, mainly in downsizing the scale of …

The significance of branched‐chain amino acids in diseases was clearly shown over the
years. This review aims to describe the available techniques for their analytical …

Understanding the metabolic abnormalities of tumors is crucial for early diagnosis,
prognosis, and treatment. Accurate identification and quantification of metabolites in …

Chemical isotope labeling liquid chromatography mass spectrometry (LC-MS) is an
emerging metabolomic strategy for the quantification and characterization of small molecular …

Histamine is a heterocyclic amine shaped by decarboxylation of the histidine. It is a
compound that lack chromophore and involatile. However, the detection of histamine is …

The ability to dissect the intracellular metabolome is vital in the study of diverse biological
systems and models. However, limited cell availability is a challenge in metabolic profiling …

The biogenic amines (BAs) synephrine (SNP), phenylephrine (PEP), tyramine (TYR), and
octopamine (OCT) may be present in products widely consumed for weight loss, muscle …

LC-MS is an indispensable tool for small molecule analysis in many fields; however, many
small molecules require chemical derivatization to improve retention on commonly used …