Communicating clocks shape circadian homeostasis
KB Koronowski, P Sassone-Corsi - Science, 2021 - science.org
BACKGROUND Life-forms ranging from bacteria to humans are programmed by circadian
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …
New insights into the circadian rhythm and its related diseases
Y Xie, Q Tang, G Chen, M Xie, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …
the molecular circadian clock which acting on coordinating internal time with the external …
Coupled network of the circadian clocks: a driving force of rhythmic physiology
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
beings, including humans, to anticipate and adapt to daily changes in their environment. In …
Prioritized research for the prevention, treatment, and reversal of chronic disease: recommendations from the lifestyle medicine research summit
Declining life expectancy and increasing all-cause mortality in the United States have been
associated with unhealthy behaviors, socioecological factors, and preventable disease. A …
associated with unhealthy behaviors, socioecological factors, and preventable disease. A …
Intercellular coupling between peripheral circadian oscillators by TGF-β signaling
AM Finger, S Jäschke, M Del Olmo, R Hurwitz… - Science …, 2021 - science.org
Coupling between cell-autonomous circadian oscillators is crucial to prevent
desynchronization of cellular networks and disruption of circadian tissue functions. While …
desynchronization of cellular networks and disruption of circadian tissue functions. While …
The concept of coupling in the mammalian circadian clock network
V Pilorz, M Astiz, KO Heinen, O Rawashdeh… - Journal of molecular …, 2020 - Elsevier
The circadian clock network regulates daily rhythms in mammalian physiology and behavior
to optimally adapt the organism to the 24-h day/night cycle. A central pacemaker, the …
to optimally adapt the organism to the 24-h day/night cycle. A central pacemaker, the …
Circadian networks in human embryonic stem cell‐derived cardiomyocytes
Cell‐autonomous circadian oscillations strongly influence tissue physiology and
pathophysiology of peripheral organs including the heart, in which the circadian clock is …
pathophysiology of peripheral organs including the heart, in which the circadian clock is …
The circadian clock of the bacterium B. subtilis evokes properties of complex, multicellular circadian systems
Circadian clocks are pervasive throughout nature, yet only recently has this adaptive
regulatory program been described in nonphotosynthetic bacteria. Here, we describe an …
regulatory program been described in nonphotosynthetic bacteria. Here, we describe an …
Circadian regulation of liver metabolism: Experimental approaches in human, rodent, and cellular models
LJ Daniels, D Kay, T Marjot… - American Journal of …, 2023 - journals.physiology.org
Circadian rhythms are endogenous oscillations with approximately a 24-h period that allow
organisms to anticipate the change between day and night. Disruptions that desynchronize …
organisms to anticipate the change between day and night. Disruptions that desynchronize …
Measuring relative coupling strength in circadian systems
Modern imaging techniques allow the monitoring of circadian rhythms of single cells.
Coupling between these single cellular circadian oscillators can generate coherent periodic …
Coupling between these single cellular circadian oscillators can generate coherent periodic …