Rapid advances in nucleic acid therapies highlight the immense therapeutic potential of
genetic therapeutics. Lipid nanoparticles (LNPs) are highly potent nonviral transfection …

RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively
target mRNA transcripts to silence protein production and combat disease. Despite the …

Polyanions. To test the impact of polyanion structure on the performance of LLNPs, we
layered LNPs with a library of four carboxylated polyanions: hyaluronate (HA), poly-L …

Ovarian tissue cryopreservation is considered to be the only means to preserve fertility for
prepubertal girls and women whose cancer treatment cannot be postponed. However …

Nanoparticulate systems have the prospect of accounting for a new making of drug delivery
systems. Nanotechnology is manifested to traverse the hurdle of both physical and …

Frontline treatment and resultant cure rates in patients with advanced ovarian cancer have
changed little over the past several decades. Here, we outline a multidisciplinary approach …

We report the development of a small molecule-based barcoding platform for pooled
screening of nanoparticle delivery. Using aryl halide-based tags (halocodes), we achieve …

Ovarian carcinoma is the leading cause of gynecological cancer-related death with still a
five-year dismal prognosis, mainly due to the late diagnosis and the emergency of …