Immunomodulatory properties of mesenchymal stromal cells: an update

L Müller, A Tunger, M Wobus, M von Bonin… - Frontiers in cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to
modulate the phenotype and functional properties of various immune cells that play an …

Biological properties and surgical applications of the human amniotic membrane

JR Munoz-Torres, SB Martínez-González… - … in Bioengineering and …, 2023 - frontiersin.org
The amniotic membrane (AM) is the inner part of the placenta. It has been used
therapeutically for the last century. The biological proprieties of AM include …

Mesenchymal stromal cell-derived secretome-based therapy for neurodegenerative diseases: overview of clinical trials

M Ghasemi, E Roshandel, M Mohammadian… - Stem cell research & …, 2023 - Springer
Background Over the past few years, mesenchymal stromal cells (MSCs) have attracted a
great deal of scientific attention owing to their promising results in the treatment of incurable …

Amniotic membrane-mesenchymal stromal cells secreted factors and extracellular vesicle-miRNAs: Anti-inflammatory and regenerative features for musculoskeletal …

E Ragni, A Papait, C Perucca Orfei… - Stem Cells …, 2021 - academic.oup.com
Human amniotic membrane-derived mesenchymal stromal cells (hAMSCs) are easily
obtained in large quantities and free from ethical concerns. Promising therapeutic results for …

Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: A translational perspective

A Papait, E Ragni, A Cargnoni, E Vertua… - Frontiers in …, 2022 - frontiersin.org
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …

Changes in the transcriptome profiles of human amnion-derived mesenchymal stromal/stem cells induced by three-dimensional culture: a potential priming strategy to …

A Gallo, N Cuscino, F Contino, M Bulati… - International Journal of …, 2022 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) are believed to function in vivo as a homeostatic
tool that shows therapeutic properties for tissue repair/regeneration. Conventionally, these …

Mesenchymal stem cells and their exocytotic vesicles

H Cai, H Guo - International Journal of Molecular Sciences, 2023 - mdpi.com
Mesenchymal stem cells (MSCs), as a kind of pluripotent stem cells, have attracted much
attention in orthopedic diseases, geriatric diseases, metabolic diseases, and sports …

Tumor microenvironment and epithelial-mesenchymal transition in bladder cancer: Cytokines in the game?

C Martins-Lima, U Chianese, R Benedetti… - Frontiers in molecular …, 2023 - frontiersin.org
Bladder cancer (BlCa) is a highly immunogenic cancer. Bacillus Calmette-Guérin (BCG) is
the standard treatment for non-muscle invasive bladder cancer (NMIBC) patients and …

[HTML][HTML] Immunomodulatory function of licensed human bone marrow mesenchymal stromal cell-derived apoptotic bodies

J Wang, E Donohoe, A Canning… - International …, 2023 - Elsevier
Abstract Background Mesenchymal stromal cells (MSCs) show great potential for
immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for …

Space radiation protection countermeasures in microgravity and planetary exploration

CA Montesinos, R Khalid, O Cristea, JS Greenberger… - Life, 2021 - mdpi.com
Background: Space radiation is one of the principal environmental factors limiting the human
tolerance for space travel, and therefore a primary risk in need of mitigation strategies to …