Pharmacogenomics and COVID-19: clinical implications of human genome interactions with repurposed drugs
OA Badary - The pharmacogenomics journal, 2021 - nature.com
The outbreak of Coronavirus disease 2019 (COVID-19) has evolved into an emergent global
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …
pandemic. Many drugs without established efficacy are being used to treat COVID-19 …
Bilirubin and endothelial function
T Maruhashi, Y Kihara, Y Higashi - Journal of atherosclerosis and …, 2019 - jstage.jst.go.jp
Bilirubin is an end product of heme degradation by heme oxygenases (HOs). At high
concentrations, bilirubin acts as a highly cytotoxic metabolite, which can cause brain …
concentrations, bilirubin acts as a highly cytotoxic metabolite, which can cause brain …
Mechanisms in endocrinology: metabolic and body composition effects of newer antiretrovirals in HIV-infected patients
S Srinivasa, SK Grinspoon - European journal of endocrinology, 2014 - academic.oup.com
In the absence of a cure, HIV-infected patients are being successfully treated with
antiretroviral therapies (ART) and living longer. Indeed, an increasing number of HIV …
antiretroviral therapies (ART) and living longer. Indeed, an increasing number of HIV …
Exercise to prevent accelerated vascular aging in people living with HIV
Given advances in antiretroviral therapy, the mortality rate for HIV infection has dropped
considerably over recent decades. However, people living with HIV (PLWH) experience …
considerably over recent decades. However, people living with HIV (PLWH) experience …
Stable patients and patients with advanced disease: consensus definitions to support sustained scale up of antiretroviral therapy
Objective As guidelines are evolving towards recommending starting antiretroviral therapy
(ART) in all HIV‐positive individuals irrespective of clinical and immunological status, HIV …
(ART) in all HIV‐positive individuals irrespective of clinical and immunological status, HIV …
HIV protease inhibitor ritonavir impairs endothelial function via reduction in adipose mass and endothelial leptin receptor‐dependent increases in NADPH oxidase 1 …
T Bruder‐Nascimento, TC Kress… - Journal of the …, 2020 - Am Heart Assoc
Background Cardiovascular disease is currently the leading cause of death in patients with
human immunodeficiency virus on combination antiretroviral therapy. Although the use of …
human immunodeficiency virus on combination antiretroviral therapy. Although the use of …
HIV, combination antiretroviral therapy, and vascular diseases in men and women
L Kovacs, TC Kress, EJ Belin de Chantemèle - Basic to Translational …, 2022 - jacc.org
Thanks to the advent of combination antiretroviral therapy (cART), people living with human
immunodeficiency virus (HIV)(PLWH) experienced a marked increase in life expectancy but …
immunodeficiency virus (HIV)(PLWH) experienced a marked increase in life expectancy but …
Arterial disease in patients with human immunodeficiency virus infection: what has imaging taught us?
With advances in antiretroviral therapy (ART), individuals with human immunodeficiency
virus (HIV) infection are living longer and increasingly die of non–HIV-related diseases, such …
virus (HIV) infection are living longer and increasingly die of non–HIV-related diseases, such …
HIV stroke risk: evidence and implications
EJ Singer, M Valdes-Sueiras… - … advances in chronic …, 2013 - journals.sagepub.com
An estimated 34 million men, women, and children are infected with human
immunodeficiency virus type 1 (HIV-1), the virus that causes acquired immunodeficiency …
immunodeficiency virus type 1 (HIV-1), the virus that causes acquired immunodeficiency …
Atazanavir/ritonavir-based combination antiretroviral therapy for treatment of HIV-1 infection in adults
CJ Achenbach, KM Darin, RL Murphy, C Katlama - Future virology, 2011 - Taylor & Francis
In the past 15 years, improvements in the management of HIV infection have dramatically
reduced morbidity and mortality. Similarly, rapid advances in antiretroviral medications have …
reduced morbidity and mortality. Similarly, rapid advances in antiretroviral medications have …