Human temperature regulation under heat stress in health, disease, and injury

MN Cramer, D Gagnon, O Laitano… - Physiological …, 2022 - journals.physiology.org
1.1. Background During exercise and with exposure to hot climatic conditions, there is
tendency for the human body to store heat and for body temperatures to rise. Changes in …

Bone fragility in diabetes: novel concepts and clinical implications

LC Hofbauer, B Busse, R Eastell, S Ferrari… - The Lancet Diabetes & …, 2022 - thelancet.com
Increased fracture risk represents an emerging and severe complication of diabetes. The
resulting prolonged immobility and hospitalisations can lead to substantial morbidity and …

Cerebral microvascular complications of type 2 diabetes: stroke, cognitive dysfunction, and depression

TT van Sloten, S Sedaghat, MR Carnethon… - The lancet Diabetes & …, 2020 - thelancet.com
Adults with type 2 diabetes are at an increased risk of developing certain brain or mental
disorders, including stroke, dementia, and depression. Although these disorders are not …

Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: Results from the International Diabetes Federation …

CC Patterson, S Karuranga, P Salpea, P Saeedi… - Diabetes research and …, 2019 - Elsevier
Aims This article describes the methods, results and limitations of the International Diabetes
Federation (IDF) Diabetes Atlas 9th edition estimates of worldwide numbers of cases of type …

Methylglyoxal, a highly reactive dicarbonyl compound, in diabetes, its vascular complications, and other age-related diseases

CG Schalkwijk, CDA Stehouwer - Physiological reviews, 2020 - journals.physiology.org
The formation and accumulation of methylglyoxal (MGO), a highly reactive dicarbonyl
compound, has been implicated in the pathogenesis of type 2 diabetes, vascular …

Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy

J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …

Microvascular dysfunction in diabetes mellitus and cardiometabolic disease

WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

Antibacterial electrospun nanofibrous materials for wound healing

Z Wang, W Hu, W Wang, Y Xiao, Y Chen… - Advanced Fiber …, 2023 - Springer
One of the leading causes of wound healing delays is bacterial infection, which limits the
process of restoring the histological and functional integrity of the skin. Electrospun …

Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy

H He, NA Fasoula, A Karlas, M Omar… - Light: Science & …, 2023 - nature.com
Being the largest and most accessible organ of the human body, the skin could offer a
window to diabetes-related complications on the microvasculature. However, skin …

Endogenous advanced glycation end products in the pathogenesis of chronic diabetic complications

MA Mengstie, E Chekol Abebe… - Frontiers in molecular …, 2022 - frontiersin.org
Diabetes is a common metabolic illness characterized by hyperglycemia and is linked to
long-term vascular problems that can impair the kidney, eyes, nerves, and blood vessels. By …