Drug resistance, fitness and compensatory mutations in Mycobacterium tuberculosis

AKA Emane, X Guo, HE Takiff, S Liu - Tuberculosis, 2021 - Elsevier
For tuberculosis to be eradicated, the transmission of Multi-Drug-Resistant and eXtensively
Drug Resistant strains of Mycobacterium tuberculosis (MDR and XDR-TB) must be …

[HTML][HTML] Emerging status of multidrug-resistant bacteria and fungi in the arabian peninsula

JF Borgio, AS Rasdan, B Sonbol, G Alhamid… - Biology, 2021 - mdpi.com
Simple Summary The incidence and developing status of multidrug-resistant bacteria and
fungi, as well as their related mortality, is reviewed by a systematic published literature …

[HTML][HTML] Origin and Global Expansion of Mycobacterium tuberculosis Complex Lineage 3

YA Shuaib, C Utpatel, TA Kohl, I Barilar, M Diricks… - Genes, 2022 - mdpi.com
Simple Summary Tuberculosis still causes 1.5 million deaths annually and is mainly caused
by Mycobacterium tuberculosis complex strains belonging to three evolutionary modern …

[HTML][HTML] Molecular epidemiology and transmission dynamics of multi-drug resistant tuberculosis strains using whole genome sequencing in the Amhara region …

A Shibabaw, B Gelaw, M Ghanem, N Legall… - BMC genomics, 2023 - Springer
Abstract Background Drug resistant Mycobacterium tuberculosis prevention and care is a
major challenge in Ethiopia. The World health organization has designated Ethiopia as one …

Highly transmitted M. tuberculosis strains are more likely to evolve MDR/XDR and cause outbreaks, but what makes them highly transmitted?

AKA Emane, X Guo, HE Takiff, S Liu - Tuberculosis, 2021 - Elsevier
Abstract Multi-Drug-Resistant strains of Mycobacterium tuberculosis (MDR-TB) are a serious
obstacle to global TB eradication. While most MDR-TB strains are infrequently transmitted, a …

[HTML][HTML] A Saudi Arabian public health perspective of tuberculosis

AA Saati, M Khurram, H Faidah, A Haseeb… - International Journal of …, 2021 - mdpi.com
Tuberculosis is a global health challenge due to its spreading potential. The Kingdom of
Saudi Arabia (KSA) faces a challenge in the spread of tuberculosis from migrant workers …

[HTML][HTML] Molecular characterization of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) isolates identifies local transmission of infection in Kuwait, a country …

NM Al-Mutairi, S Ahmad, EM Mokaddas - European Journal of Medical …, 2019 - Springer
Background Increasing incidence of multidrug-resistant Mycobacterium tuberculosis
infections is hampering global tuberculosis control efforts. Kuwait is a low-tuberculosis …

Mycobacterium tuberculosis Sub-Lineage 4.2.2/SIT149 as Dominant Drug-Resistant Clade in Northwest Ethiopia 2020–2022: In-silico Whole-Genome Sequence …

D Mekonnen, A Munshea, E Nibret… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Drug resistance (DR) in Mycobacterium tuberculosis complex (MTBC) is mainly
associated with certain lineages and varies across regions and countries. The Beijing …

[HTML][HTML] Clusters of drug-resistant Mycobacterium tuberculosis detected by whole-genome sequence analysis of nationwide sample, Thailand, 2014–2017

D Nonghanphithak, A Chaiprasert… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Multidrug-resistant tuberculosis (MDR TB), pre-extensively drug-resistant tuberculosis (pre-
XDR TB), and extensively drug-resistant tuberculosis (XDR TB) complicate disease control …

Prevalence of multidrug-resistant tuberculosis in Dalian, China: a Retrospective Study

L Du, Y Zhang, X Lv, Y Duan, X Shi, H Ji… - Infection and Drug …, 2021 - Taylor & Francis
Purpose Multidrug-resistant tuberculosis (MDR-TB) is the cause of serious health and
economic burdens worldwide. The present study aimed to explore the initial and acquired …