Tetrazoles via multicomponent reactions

CG Neochoritis, T Zhao, A Domling - Chemical reviews, 2019 - ACS Publications
Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

Recent advances in synthesis and medicinal chemistry of benzodiazepines

N Arora, P Dhiman, S Kumar, G Singh, V Monga - Bioorganic Chemistry, 2020 - Elsevier
Benzodiazepines (BZDs) represent a diverse class of bicyclic heterocyclic molecules. In the
last few years, benzodiazepines have emerged as potential therapeutic agents. As a result …

[HTML][HTML] An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds

HE Hashem, Y El Bakri - Arabian Journal of Chemistry, 2021 - Elsevier
Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention
in the field of contemporary medicinal chemistry because of its wide array of …

Immobilized nickel boride nanoparticles on magnetic functionalized multi-walled carbon nanotubes: a new nanocomposite for the efficient one-pot synthesis of 1, 4 …

FM Aminzadeh, B Zeynizadeh - Nanoscale Advances, 2023 - pubs.rsc.org
In this study, a new magnetic nanocomposite consisting of Ni2B nanoparticles anchored on
magnetic functionalized multi-walled carbon nanotubes (Fe3O4/f-MWCNT/Ni2B) was …

[HTML][HTML] A Review on Benzimidazole Heterocyclic Compounds: Synthesis and Their Medicinal Activity Applications

LA Mohammed, MA Farhan, SA Dadoosh… - …, 2023 - thieme-connect.com
Benzimidazole is a heterocyclic compound that contains two nitrogen atoms and is formed
by fusing a benzene ring with an imidazole. Benzimidazole and its derivatives are prepared …

Study of novel triazolo-benzodiazepine analogues as antidepressants targeting by molecular docking and ADMET properties prediction

A Belhassan, H Zaki, M Benlyas, T Lakhlifi… - Heliyon, 2019 - cell.com
In this study, we have selected a series of a new family of molecules bearing Triazolo-
benzodiazepines, an eleven membered heterocyclic ring has been studied for …

Design of mononuclear, binuclear and polynuclear molybdenum (VI) complexes based on ONO benzoylacetone derived enaminones and their in vitro biological …

J Pisk, L Bilić, M Đaković, D Cvijanović, V Damjanović… - Polyhedron, 2018 - Elsevier
Molybdenum (VI) complexes of different nuclearity, mononuclear,[MoO 2 (L 1 or 2)(MeOH)]·
MeOH (1· MeOH and 2· MeOH),[MoO 2 (L 1 or 2)(D)][D= pyridine,(1a and 2a), 3 …

Design, synthesis and anticancer activity of N-(1-(4-(dibenzo [b, f][1, 4] thiazepin-11-yl) piperazin-1-yl)-1-oxo-3-phenylpropan-2-yl derivatives

MR Gudisela, N Srinivasu, C Mulakayala… - Bioorganic & Medicinal …, 2017 - Elsevier
Abstract Novel N-(1-(4-(dibenzo [b, f][1, 4] thiazepin-11-yl) piperazin-1-yl)-1-oxo-3-
phenylpropan-2-yl derivatives were designed, synthesized and their chemical structures …

(Z)-Stereoselective Synthesis of Mono- and Bis-heterocyclic Benzimidazol-2-ones via Cascade Processes Coupled with the Ugi Multicomponent Reaction

Z Xu, G Martinez-Ariza, AP Cappelli… - The Journal of …, 2015 - ACS Publications
Several novel cascade reactions are herein reported that enable access to a variety of
unique mono-and bis-heterocyclic scaffolds. The sequence of cascade events are mediated …

Novel family of fused tricyclic [1, 4] diazepines: Design, synthesis, crystal structures and molecular docking studies

A Adamski, D Kruszka, Z Dutkiewicz, M Kubicki… - Tetrahedron, 2017 - Elsevier
An efficient one-pot strategy for the synthesis of a new family of imidazo [1, 4] diazepines has
been developed and its mechanism has been proposed, which follows a seven-membered …